Protein Alignment Spt and ctnna2

DIOPT Version :10

• Sequence 1: NP_610423.3
• Gene: Spt / 35889
• FlyBaseID: FBgn0033348
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001090774.1
• Gene: ctnna2 / 100037860
• XenbaseID: XB-GENE-5955201
• Length: 966
• Species: Xenopus tropicalis
• Alignment Length: 350
• Identity: 63/350 - (18%)
• Similarity: 117/350 - (33%)
• Gaps: 102/350 - (29%)

  Fly    10 ACLLILNRNNA----AAANWLNDLCAVLLEFA-TLAHSSFCSQGQSECSELVCLCLSQIMICIRQ 69
            ||.:..|....    .||..::.||..::..| |||........|............|:.:....
 Frog   447 ACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEA 511

  Fly    70 VENTMKLECGTTVSVSHQYFLDRIRWCL----------------------KRLMHLYSEESSS-- 110
            |::...::  ..:|||..:.|:.:..|:                      .|::|:.:.|..:
 Frog   512 VDDITSVD--DFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYE 574

  Fly   111 ----------------EAVAPERSFLKLVDGALDCL-AQFTSHSEEN--TDTSNCP--------- 147
                            |.|.|.  |.:.|:.|::.| |......|||  .|.|...
 Frog   575 AGVYTEKVLDATKLLCETVMPR--FAEQVEFAIEALSANIPQPFEENEFIDASRLVYDGVRDIRK 637

  Fly   148 -----KTPKEVLPLSQKLRANID-------------LILGQSLGFANVALSQDKRALSALCQKVI 194
                 :||:|:...|...:.:.|             ||.|||.......|.|:::|      |:.
 Frog   638 AVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKA------KIA 696

  Fly   195 RECNAFQEECKESFSANYLSTLKLRAMTMEQAIYQLEDFINDALLRLVFTCFLDFEKFSVDKIRA 259
            .:...|.:|..:                ::..:.:.:|..||.::.....|.:..|.....:.:.
 Frog   697 EQVEIFHQEKSK----------------LDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKG 745

  Fly   260 LLRNSPDNDDLADEFIADFDVNIDR 284
            .|:|:.|..:.|.: ||:....:|:
 Frog   746 PLKNTSDVINAAKK-IAEAGSRMDK 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spt	NP_610423.3	Serendipity_A	1..468	CDD:368466	63/349 (18%)
ctnna2	NP_001090774.1	Vinculin	18..927	CDD:460040	63/349 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	924..952