DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgi and AT5G42740

DIOPT Version :9

Sequence 1:	NP_523663.1	Gene:	Pgi / 35886	FlyBaseID:	FBgn0003074	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_001332180.1	Gene:	AT5G42740 / 834283	AraportID:	AT5G42740	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	251/547 - (45%)
Similarity:	336/547 - (61%)	Gaps:	40/547 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QEYYDSKG-----KDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDLLLTLA 77
            :.:.|.||     |..:::|| :.|:.|.....:..    || :|||||:.|...|..|.||.||
plant    12 EAWKDLKGHVEDIKKTHLRDL-MSDANRCQSMMMEF----DG-LLLDYSRQRATVETMDKLLNLA 70

  Fly    78 KVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEFTNMVI 142
            |..::......||:|:|||.||||:|||.|||......:..|..:|:|:|...|..:|||::.:.
plant    71 KASQLTEKISRMFNGEHINSTENRSVLHVALRAPKDAVIKADGMNVVPEVWNVLDKIKEFSDKIR 135

  Fly   143 SGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALK------PYGKGLHSHFVSNIDGTHLAEVLK 201
            ||.|.|.|||.:.||:.||||||.||||.|..||:      ...||....|::|||...:|..:.
plant   136 SGSWVGATGKPLKDVIAIGIGGSFLGPLFVHTALQTDPEALESAKGRQLRFLANIDPVDVARNIS 200

  Fly   202 KVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTN 266
            .:|.||||.:|.||||||.||:.||.:.:.|:.. :....:||||.||:|||...|.:||||..|
plant   201 GLNPETTLVVVVSKTFTTAETMLNARTLREWITA-ALGASAVAKHMVAVSTNLALVEKFGIDPNN 264

  Fly   267 MFGFWDWVGGRYSLWSAIG-LSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVW 330
            .|.||||||||||:.||:| |.:.|..||...|:.|.||..:|.||::||||||.||:|.||.||
plant   265 AFAFWDWVGGRYSVCSAVGVLPLSLQYGFSMVEKFLKGASSIDQHFQSTPFEKNIPVLLGLLSVW 329

  Fly   331 YSNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAF 395
            ..:|......|:|||.|.|.:||.:.||..||||||.||..|.|:.:.||.|.:|||||||||:|
plant   330 NVSFLGYPARAILPYSQALEKFAPHIQQVSMESNGKGVSIDGLPLPFETGEIDFGEPGTNGQHSF 394

  Fly   396 YQLIHQGTRLIPCDFIAPAQTHNPI-AGGK---HHKILLSNFLAQTEALMAGKTVDEARTELSKA 456
            ||||||| |:||||||...::..|: ..|:   :|..|:|||.||.:||..|||.::.:.|
plant   395 YQLIHQG-RVIPCDFIGIVKSQQPVYLKGEVVSNHDELMSNFFAQPDALAYGKTPEQLQKE---- 454

  Fly   457 GLCGNELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVEL 521
                |..:||:|||.|.||||:.|:::.:::.:.:|.|:|:|||::.|||.:|.|||||||||||
plant   455 ----NVSENLIPHKTFSGNRPSLSLLLPELTAYNVGQLLAIYEHRVAVQGFVWGINSFDQWGVEL 515

  Fly   522 GKQLAKAIEPELDHCNEVSTHDSSTNG 548
            ||.||..:..:|        |.|.|.|
plant   516 GKVLATQVRKQL--------HSSRTQG 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgi	NP_523663.1	pgi	7..556	CDD:234679	251/547 (46%)
		SIS_PGI_1	128..290	CDD:240146	80/168 (48%)
		SIS_PGI_2	338..529	CDD:240147	99/194 (51%)
AT5G42740	NP_001332180.1	PLN02649	1..559	CDD:215351	251/547 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	434	1.000	Domainoid score	I108
eggNOG	1	0.900	-	-		E1_COG0166
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H145
Inparanoid	1	1.050	444	1.000	Inparanoid score	I402
OMA	1	1.010	-	-		QHG54138
OrthoDB	1	1.010	-	-		D446616at2759
OrthoFinder	1	1.000	-	-		FOG0003701
OrthoInspector	1	1.000	-	-		oto2955
orthoMCL	1	0.900	-	-		OOG6_100716
Panther	1	1.100	-	-	LDO	PTHR11469
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2569
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840