Protein Alignment Pgi and gpi-1

DIOPT Version :10

• Sequence 1: NP_523663.1
• Gene: Pgi / 35886
• FlyBaseID: FBgn0003074
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001021838.1
• Gene: gpi-1 / 173227
• WormBaseID: WBGene00013597
• Length: 586
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 376/549 - (68%)
• Similarity: 436/549 - (79%)
• Gaps: 1/549 - (0%)

  Fly     8 LNQEAAFQKLQEYYDSKGKDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDL 72
            |:|:|.|.:|:.:.::..||..:.:||.||..||.|:: ||....||:.|.|:|||||.||.:.|
 Worm    38 LSQDATFVELKRHVEANEKDAQLLELFEKDPARFEKFT-RLFATPDGDFLFDFSKNRITDESFQL 101

  Fly    73 LLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEF 137
            |:.|||.|.|..:|:||||.:.||.||||||||.|||||...|:|||.|||||||...|||||||
 Worm   102 LMRLAKSRGVEESRNAMFSAEKINFTENRAVLHVALRNRANRPILVDGKDVMPDVNRVLAHMKEF 166

  Fly   138 TNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGKGLHSHFVSNIDGTHLAEVLKK 202
            .|.:|||.|.|.|||:|||||||||||||||||||||:||.|..|.:.|||||:||||:|||.||
 Worm   167 CNEIISGSWTGYTGKKITDVVNIGIGGSDLGPLMVTESLKNYQIGPNVHFVSNVDGTHVAEVTKK 231

  Fly   203 VNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTNM 267
            :|.||||||:||||||||||||||.:||.|.|..:.:..:|||||||||||..|..|||||..||
 Worm   232 LNAETTLFIIASKTFTTQETITNAETAKEWFLAKAGDAGAVAKHFVALSTNVTKAVEFGIDEKNM 296

  Fly   268 FGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWYS 332
            |.|||||||||||||||||||.:.|||:|:|:|||||..:|.||..||.|||.|||||::||.|:
 Worm   297 FEFWDWVGGRYSLWSAIGLSIAVHIGFDNYEKLLDGAFSVDEHFVNTPLEKNIPVILAMIGVLYN 361

  Fly   333 NFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFYQ 397
            |.:.||||||||||||:|||||||||||||||||||::.|:.|.|||||||||||||||||||||
 Worm   362 NIYGAETHALLPYDQYMHRFAAYFQQGDMESNGKFVTRHGQRVDYSTGPIVWGEPGTNGQHAFYQ 426

  Fly   398 LIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGNE 462
            ||||||||||.|||||.:|.|||.||.||:|||:||||||||||.|||...|..||..:|:....
 Worm   427 LIHQGTRLIPADFIAPVKTLNPIRGGLHHQILLANFLAQTEALMKGKTAAVAEAELKSSGMSPES 491

  Fly   463 LDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLAK 527
            :..:||||||.||:||.|||:..|:|||||||||.||||||||||||||.|:|||||||||||||
 Worm   492 IAKILPHKVFEGNKPTTSIVLPVVTPFTLGALIAFYEHKIFVQGIIWDICSYDQWGVELGKQLAK 556

  Fly   528 AIEPELDHCNEVSTHDSSTNGLINFIKAN 556
            .|:|||...:.|::||:||||||.|||.|
 Worm   557 VIQPELASADTVTSHDASTNGLIAFIKNN 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgi	NP_523663.1	pgi	7..556	CDD:234679	375/547 (69%)
gpi-1	NP_001021838.1	pgi	34..583	CDD:234679	373/545 (68%)