Protein Alignment Pgi and Gpi1

DIOPT Version :10

• Sequence 1: NP_523663.1
• Gene: Pgi / 35886
• FlyBaseID: FBgn0003074
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_032181.2
• Gene: Gpi1 / 14751
• MGIID: 95797
• Length: 558
• Species: Mus musculus
• Alignment Length: 548
• Identity: 378/548 - (68%)
• Similarity: 438/548 - (79%)
• Gaps: 2/548 - (0%)

  Fly     8 LNQEAAFQKLQEYYDSKGKDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDL 72
            |.:...||||.|::.:...:|.:::||..|.:||:.:||.|:| |.|.||:|||||.:|.||..:
Mouse     4 LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNT-NHGHILVDYSKNLVNKEVMQM 67

  Fly    73 LLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEF 137
            |:.|||.|.|.||||.||||..||.||||||||.|||||...|:.||.|||||:|...|..||.|
Mouse    68 LVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSF 132

  Fly   138 TNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGK-GLHSHFVSNIDGTHLAEVLK 201
            ...|.||.|:|.|||.|||::|||||||||||||||||||||.| |....|||||||||:|:.|.
Mouse   133 CQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLA 197

  Fly   202 KVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTN 266
            .::.||:|||:||||||||||||||.:||.|.||.:|:|.:|||||||||||..||.|||||..|
Mouse   198 SLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQN 262

  Fly   267 MFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWY 331
            ||.|||||||||||||||||||.|.:||::|||||.|||:||.||..||.||||||:|||||:||
Mouse   263 MFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWY 327

  Fly   332 SNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFY 396
            .|.:..|||||||||||:|||||||||||||||||:::|||..|.:.||||||||||||||||||
Mouse   328 INCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFY 392

  Fly   397 QLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGN 461
            |||||||::|||||:.|.||.:||..|.||||||:||||||||||.||..:|||.||..||....
Mouse   393 QLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPE 457

  Fly   462 ELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLA 526
            :|:.|||||||.|||||||||..|::||.||||||:||||||||||:||||||||||||||||||
Mouse   458 DLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLA 522

  Fly   527 KAIEPELDHCNEVSTHDSSTNGLINFIK 554
            |.|||||:..:.|::|||||||||:|||
Mouse   523 KKIEPELEGSSAVTSHDSSTNGLISFIK 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgi	NP_523663.1	pgi	7..556	CDD:234679	378/548 (69%)
Gpi1	NP_032181.2	pgi	1..554	CDD:234679	378/548 (69%)