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Protein Alignment Pgi and Gpi1

DIOPT Version :9

Sequence 1:	NP_523663.1	Gene:	Pgi / 35886	FlyBaseID:	FBgn0003074	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_032181.2	Gene:	Gpi1 / 14751	MGIID:	95797	Length:	558	Species:	Mus musculus

Alignment Length:	548	Identity:	378/548 - (68%)
Similarity:	438/548 - (79%)	Gaps:	2/548 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LNQEAAFQKLQEYYDSKGKDLNIKDLFVKDSKRFSKYSLRLHTQNDGEILLDYSKNRINDEVWDL 72
            |.:...||||.|::.:...:|.:::||..|.:||:.:||.|:| |.|.||:|||||.:|.||..:
Mouse     4 LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNT-NHGHILVDYSKNLVNKEVMQM 67

  Fly    73 LLTLAKVRRVNAARDAMFSGQHINITENRAVLHTALRNRGTDPVLVDDKDVMPDVRAELAHMKEF 137
            |:.|||.|.|.||||.||||..||.||||||||.|||||...|:.||.|||||:|...|..||.|
Mouse    68 LVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSF 132

  Fly   138 TNMVISGVWRGCTGKQITDVVNIGIGGSDLGPLMVTEALKPYGK-GLHSHFVSNIDGTHLAEVLK 201
            ...|.||.|:|.|||.|||::|||||||||||||||||||||.| |....|||||||||:|:.|.
Mouse   133 CQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLA 197

  Fly   202 KVNYETTLFIVASKTFTTQETITNATSAKTWLLEHSKEPESVAKHFVALSTNKEKVTEFGIDSTN 266
            .::.||:|||:||||||||||||||.:||.|.||.:|:|.:|||||||||||..||.|||||..|
Mouse   198 SLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQN 262

  Fly   267 MFGFWDWVGGRYSLWSAIGLSICLSIGFENFEQLLDGAHFMDNHFKTTPFEKNAPVILALLGVWY 331
            ||.|||||||||||||||||||.|.:||::|||||.|||:||.||..||.||||||:|||||:||
Mouse   263 MFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWY 327

  Fly   332 SNFFKAETHALLPYDQYLHRFAAYFQQGDMESNGKFVSKSGKPVKYSTGPIVWGEPGTNGQHAFY 396
            .|.:..|||||||||||:|||||||||||||||||:::|||..|.:.||||||||||||||||||
Mouse   328 INCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFY 392

  Fly   397 QLIHQGTRLIPCDFIAPAQTHNPIAGGKHHKILLSNFLAQTEALMAGKTVDEARTELSKAGLCGN 461
            |||||||::|||||:.|.||.:||..|.||||||:||||||||||.||..:|||.||..||....
Mouse   393 QLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPE 457

  Fly   462 ELDNLLPHKVFVGNRPTNSIVVKKVSPFTLGALIALYEHKIFVQGIIWDINSFDQWGVELGKQLA 526
            :|:.|||||||.|||||||||..|::||.||||||:||||||||||:||||||||||||||||||
Mouse   458 DLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLA 522

  Fly   527 KAIEPELDHCNEVSTHDSSTNGLINFIK 554
            |.|||||:..:.|::|||||||||:|||
Mouse   523 KKIEPELEGSSAVTSHDSSTNGLISFIK 550

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.