DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30349 and SPCC1450.03

DIOPT Version :9

Sequence 1:	NP_610421.1	Gene:	CG30349 / 35885	FlyBaseID:	FBgn0050349	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_588302.1	Gene:	SPCC1450.03 / 2539316	PomBaseID:	SPCC1450.03	Length:	240	Species:	Schizosaccharomyces pombe

Alignment Length:	194	Identity:	43/194 - (22%)
Similarity:	84/194 - (43%)	Gaps:	38/194 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   430 LLMQALHSKDQAMIQAVLSTQDPETIQLTLDRLPLDYVNPLVNELSILLQGKHASVRSALRWLHA 494
            ||.|.|:..|..::...:...|        ..:..|....|:..:.|.:|      .|...|||.
pombe    20 LLEQCLNCSDVGVVSNTVRNMD--------GTIAADLARTLIPAMLINMQ------PSLAIWLHW 70

  Fly   495 LTSTH----TSVLMSEDK-EALREKLAVCLGVAEQRMHCLSEALQITGRVNLIINQMKRNADNHL 554
            :..||    |:|:..:|. ..|.|||.       |..|.:::...::|::|::::|
pombe    71 IIVTHGGYLTTVMDLQDSLVQLHEKLV-------QSAHLMTKIFSLSGKLNMVLSQ--------- 119

  Fly   555 NDNKALILDEDPDEPDPEAETNWSDLEEDQPGSPKSPLEDELVADDDLATD-DGNADADTDSDV 617
            .:.:...||...::.:.|.|.::.|.:.|:.|.....:::  ..:||:..| :.||||..:|::
pombe   120 EEMRQRRLDFSSEDGEEEEENDYIDEDVDEAGYDIEVVDE--AENDDMDNDLEANADAFDESNL 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30349	NP_610421.1	WD40	<7..237	CDD:225201
		WD40 repeat	7..50	CDD:293791
		WD40	11..>230	CDD:295369
		WD40 repeat	72..108	CDD:293791
		WD40 repeat	117..151	CDD:293791
		WD40 repeat	159..191	CDD:293791
		WD40 repeat	200..241	CDD:293791
		WD40 repeat	248..273	CDD:293791
		Utp12	439..534	CDD:281932	21/99 (21%)
SPCC1450.03	NP_588302.1	Utp12	18..116	CDD:281932	27/116 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002889
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900