DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30349 and T10B5.3

DIOPT Version :9

Sequence 1:	NP_610421.1	Gene:	CG30349 / 35885	FlyBaseID:	FBgn0050349	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_503519.2	Gene:	T10B5.3 / 178667	WormBaseID:	WBGene00020389	Length:	295	Species:	Caenorhabditis elegans

Alignment Length:	304	Identity:	72/304 - (23%)
Similarity:	129/304 - (42%)	Gaps:	53/304 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 AKKKGKEQPGYQAAT------KVQKPIVN---QKNVEYNSALPISQKKVQNEVPMEAR------- 406
            |:::...:....|.|      |::.|:||   ..|....:...:|:.:.:...|:..|
Worm     2 ARERKARKSNVAAVTSPATPEKIESPVVNGHSHINGSLRNGKKLSESEKEANKPLGDREKEPATP 66

  Fly   407 LEHLKIQGTKLSGGKLLTQSKTQLLMQALHSKDQAMIQAVLSTQDPETIQLTLDRLPLDYVNPLV 471
            ...||...|..|||    .|:..||.|.:.:.|.|.|.:|:...:.|.|..||..|....|.||:
Worm    67 TSELKKGKTSGSGG----GSQCVLLTQGIMANDSAKIDSVIRNLNSEIIHATLRDLQPMQVLPLL 127

  Fly   472 NELSILLQGKHAS-VRSALRWLHALTSTHTSVLMSEDKEALREKLAVCLGVAEQRMHCLSEALQI 535
            ..:...|:.::|: :|..:||.....|.|...|.|...  |.:::...:|....|:....:.|.:
Worm   128 KIIESRLKTRNAADIRPTIRWAQIAFSIHMPYLSSLPN--LEKEIGGLIGWLRSRVGHHRDLLAL 190

  Fly   536 TGRVNLIINQMKRNADNHLNDNKALI-----LDED--------PDEPDPEAETNW---SDLEEDQ 584
            .|:::.|.:.:||..:|.:...:.|:     ||.|        .|:....:|.:|   ::|:||:
Worm   191 HGKISTIADLIKRRTNNVVIVQQPLVVFNNDLDSDSEDFDTIGSDDDGESSEDDWWEDNELKEDE 255

  Fly   585 PGSPKSPLEDELVADDDLATDDGNADAD--------TDSDVSMD 620
            ..:...  :||    ||..:||...|||        :::|..|:
Worm   256 EENQDD--DDE----DDNDSDDSEMDADSAESGGSGSENDEDME 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30349	NP_610421.1	WD40	<7..237	CDD:225201
		WD40 repeat	7..50	CDD:293791
		WD40	11..>230	CDD:295369
		WD40 repeat	72..108	CDD:293791
		WD40 repeat	117..151	CDD:293791
		WD40 repeat	159..191	CDD:293791
		WD40 repeat	200..241	CDD:293791
		WD40 repeat	248..273	CDD:293791
		Utp12	439..534	CDD:281932	24/95 (25%)
T10B5.3	NP_503519.2	Utp12	94..191	CDD:367767	25/98 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002889
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102917
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1622
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.700