DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8252 and Akap14

DIOPT Version :9

Sequence 1:	NP_610420.1	Gene:	CG8252 / 35884	FlyBaseID:	FBgn0033344	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_067735.1	Gene:	Akap14 / 60332	RGDID:	708510	Length:	502	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	55/263 - (20%)
Similarity:	87/263 - (33%)	Gaps:	70/263 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PPSPGSGVPALGPG-GALPIAIIPSISSLVNQCNKPACDDADMQCIIDLIEGTLCEAVAIIESDP 75
            ||:|.:...::.|. ...|:|::..::..|.|                  :..:.|.....|..|
  Rat   238 PPAPVAPPASVAPPVPDAPVALVAPVAPQVKQ------------------KIRVSEVKRKKEVPP 284

  Fly    76 RGLFIYNFPKKQKMSSI---------SLISSVFTDTIVANG----------EDDPSITNHYTGGL 121
            |      .|:.::|..:         .::|.:...|.|.:|          |..|::.......:
  Rat   285 R------VPQLKEMKVVLFTPEIKEKKVVSEIKEKTQVIDGKEKLIVPDVKEKKPAVVEKKDERM 343

  Fly   122 GISADSVSSGL----------AR------KMLTIGDFEYSNAIADIRDFVSRWELSPDTKCVVIS 170
            ...|.:|..|:          ||      |.||.|:|........|..|||.||.  ..:.|..:
  Rat   344 NEIARTVVEGVLAASVQFVEEARNPIKNIKWLTHGEFTAEKGRKQIEKFVSTWEF--QNRWVYYA 406

  Fly   171 NPIRHEVAKKGTI----LFVDAHFSRPTPRCPNPLAVAKVRFIISLSKILLKHYPVMITYRFEGY 231
            :.|.    ||..|    ......:|.||...|.....|...|.|..:|......||.::|.||..
  Rat   407 DFIE----KKDLIHSFHYIYRVRWSAPTAVRPMARVSANAYFTIKFNKSKPADMPVDVSYIFENS 467

  Fly   232 NTL 234
            ..|
  Rat   468 ELL 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8252	NP_610420.1	AKAP28	136..264	CDD:291158	29/103 (28%)
Akap14	NP_067735.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..84
		8 X 4 AA repeat of P-X-X-P	199..265		6/26 (23%)
		RII-binding	258..378		23/143 (16%)
		AKAP28	374..494	CDD:291158	29/103 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BW5E
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109355
Panther	1	1.100	-	-	LDO	PTHR35075
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900