DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT8 and cct3

DIOPT Version :9

Sequence 1:	NP_610418.1	Gene:	CCT8 / 35882	FlyBaseID:	FBgn0284436	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_989339.1	Gene:	cct3 / 394965	XenbaseID:	XB-GENE-6250478	Length:	548	Species:	Xenopus tropicalis

Alignment Length:	545	Identity:	156/545 - (28%)
Similarity:	271/545 - (49%)	Gaps:	31/545 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VSQMLK--DGARMYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVTSDAGTIM 73
            :||.:|  .|.::.||       ||:|.|..|..:|:..||..|.||:::.:....:|:|...|:
Frog     9 LSQNIKRESGRKVQSG-------NINAAKTIADIIRTCLGPRAMMKMLLDPMGGIVMTNDGNAIL 66

  Fly    74 RELDVEHPAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAEISDGYEKALEK 138
            ||:.|:|||||.::..|:.||.||||||..|::|||.:|..||:.|...:....:...|.|||:.
Frog    67 REIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEQFLEQQMHPTVVISAYRKALDD 131

  Fly   139 ALEILPNLVSHKIEDYRNVEKVKEVLRTSIMSKQYGQ-EDFLNDLVSKACVSI-LPDEGTFNVD- 200
            .:..|.. :|..: |..:.|.:.:::.:::.:|...: .|....:...|..:: |.:.|...:|
Frog   132 MVSTLKE-ISTPV-DTNDRELMLKIINSAVNTKAIKRWADMACGIALDAVKTVELEENGRKEIDI 194

  Fly   201 --NIRICKILGSGLTKSEVVRGMVFKRFVEGDVTY------AEKAKIVIFSCPVDIIQTETKGTV 257
              ..::.||.|..:..|.|:||::    |..|||:      .:..:||:..|.::..:.|::..:
Frog   195 KKYAKVEKIPGGIIEDSCVLRGVM----VNKDVTHPKMRRLIKNPRIVLLDCSLEYKKGESQTEI 255

  Fly   258 LIKSADELLSFSSGEESLLESQIKAIADAGVKVVVAGGKVGDMALHFLNKYGLMAVRLNSKFDLR 322
            .|...::.......||..::...:.|......||:....:.|:|.|:|.|..:.|:|...|.|..
Frog   256 EITREEDFARILQMEEEYIQQVCEDIIRLKPDVVITEKGISDLAQHYLVKANITAIRRVRKTDNN 320

  Fly   323 RLSRSVNATVLPRITTPSQEELGY-CDKVCIEELGDTTIVAFRNEGKDSRIATVVIRGATDNFMD 386
            |::|:..|.:..|.....:|::|. .....|:::|| ....|..|.||.:..|:|:|||:...:.
Frog   321 RIARACGARIGSRTDELREEDVGTGAGLFEIKKIGD-EYFTFITECKDPKACTIVLRGASKEILA 384

  Fly   387 DIERALDDAINNFKCLTRDGRYLPGAGATEIELATQLSAYADTLPGLDQYAVRKFANALEVFPKA 451
            ::||.|.||:...:.:..|...:||.||.|:.:|..|:..:.|:.|::|:..|..|.||||.|:.
Frog   385 EVERNLQDAMQVCRNVVIDPHLVPGGGAAEMSVAHILTEKSKTMTGVEQWPYRAVAQALEVIPRT 449

  Fly   452 LAENSGINGTEIVNQLYLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKFWGLKYAVGAA 516
            |.:|.|.:...::..|...|..|..:|.|.|.||  ...:|..:..:::....|....|.||..|
Frog   450 LVQNCGASTIRVLTSLRAKHTQEGCQTWGVDGEA--GVLVDMKELGIWEPLAVKLQTYKTAVETA 512

  Fly   517 ATILKVDQIIMA-KRAGGPKVRQAA 540
            ..:|::|.|:.. ||.|....||.|
Frog   513 ILLLRIDDIVSGHKRKGEDHGRQPA 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	146/521 (28%)
CCT8	NP_610418.1	Cpn60_TCP1	40..529	CDD:278544	140/501 (28%)
cct3	NP_989339.1	chap_CCT_gamma	5..528	CDD:274085	151/534 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010