Protein Alignment CCT8 and Cct6b

DIOPT Version :10

• Sequence 1: NP_610418.1
• Gene: CCT8 / 35882
• FlyBaseID: FBgn0284436
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_001014250.1
• Gene: Cct6b / 363658
• RGDID: 1359453
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 135/532 - (25%)
• Similarity: 250/532 - (46%)
• Gaps: 36/532 - (6%)

  Fly    26 EEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVTSDAGTIMRELDVEHPAAKLIVMAS 90
            :.|:..||.|.:.....:|.:.||.|..||:::......:|.|...::.|:.::||.|.:|...:
  Rat    17 QAALAVNICAARGLQDVLRPSLGPKGALKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASIIAKVA 81

  Fly    91 QMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAEISDGYEKALEKALEILPNLVSHKIEDYR 155
            ..||...||||...|::.|.||:.|:..:..|:....|::|::.|..||||:|..:   |::...
  Rat    82 AAQDHITGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFDVAKTKALEVLDKI---KVQKEM 143

  Fly   156 NVEKVKEVLRTSIMSKQYGQ-EDFLNDLVSKACVSILPDEGTFNVDNIRICKILGSGLTKSEVVR 219
            ..|.:.:|.|||:.:|.:.: .|.|.:.|..:.::|.......::..:.|.::.....|.:::||
  Rat   144 KREMLLDVARTSLRTKVHTELADILTEAVVDSVLAIRRPGIPIDLFMVEIVEMRHKSETDTQLVR 208

  Fly   220 GMV---------FKRFVEGDVTYAEKAKIVIFSCPVDIIQTETKGTVLIKSADELLSFSSGEESL 275
            |:|         .|:.|       :.|.|:|.:..::..:||.......|:.:|.......|...
  Rat   209 GLVLDHGARHPRMKKQV-------QDAYILICNVSLEYEKTEVSSGFFYKTVEEKEKLVKAERKF 266

  Fly   276 LESQIKAIADAGVKVVVAGGK---------VGDMALHFLNKYGLMAVRLNSKFDLRRLSRSVNAT 331
            :|.:::.|.|...||.....|         :..::|..|.|:.::|:|...:.:|.||:.:....
  Rat   267 IEDRVQKIIDLKQKVCAESNKGFVVINQKGIDPVSLEMLAKHNIVALRRAKRRNLERLTLACGGL 331

  Fly   332 VLPRITTPSQEELGYCDKVCIEELGDTTIVAFRNEGKDSRIATVVIRGATDNFMDDIERALDDAI 396
            .:..:...|:|.||:...|....||:... .|..:..:....|::::|...:.:..|:.||.|.:
  Rat   332 AVNSLEDLSEECLGHAGLVFEYTLGEEKF-TFIEDCVNPLSVTLLVKGPNKHTLIQIKDALRDGL 395

  Fly   397 NNFKCLTRDGRYLPGAGATEIELATQLSAYADTLPGLDQYAVRKFANALEVFPKALAENSGINGT 461
            ...|....||..:|||||.|:.:|..|..|...:.|..:..::.||:||.:.||.||:|||.:..
  Rat   396 RAVKNAIEDGCVVPGAGAVEVAIAEALVNYKHCVQGRARLGIQAFADALLIIPKVLAQNSGYDLQ 460

  Fly   462 EIVNQLYLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKFWGLKYAVGAAATILKVDQII 526
            |.:.::...| .|:.:.:|.|:..  ...:...:|.::|.|..|...|......|..:|.||:|:
  Rat   461 ETLIKIQTKH-AESKELVGIDLNT--GEPMVAAEAGIWDNYCVKKHILHSCTVIATNVLLVDEIM 522

  Fly   527 MAKRAGGPKVRQ 538
               |||...:|:
  Rat   523 ---RAGMSSLRE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	131/521 (25%)
Cct6b	NP_001014250.1	chap_CCT_zeta	3..530	CDD:274088	134/529 (25%)