DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT8 and cct5

DIOPT Version :9

Sequence 1:	NP_610418.1	Gene:	CCT8 / 35882	FlyBaseID:	FBgn0284436	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_997778.1	Gene:	cct5 / 322258	ZFINID:	ZDB-GENE-030131-977	Length:	541	Species:	Danio rerio

Alignment Length:	524	Identity:	165/524 - (31%)
Similarity:	270/524 - (51%)	Gaps:	26/524 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KDGARMYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVTSDAGTIMRELDVEH 80
            :|.....:|| ||:..:|.|.|..|.|:|::.||||::||:::...:..||:|..||:..:||:|
Zfish    22 QDKKSRLTGL-EALKSHILAAKAVANTLRTSLGPNGLDKMMVDKDGEVTVTNDGATILSMMDVDH 85

  Fly    81 PAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAEISDGYEKALEKALEILPN 145
            ..|||:|..|:.||.|:||||..||||||||||.||:||..||....|:|||::|.:.|:|.|..
Zfish    86 QIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEQAEQLLDRGIHPIRIADGYDQAAKIAIEQLDK 150

  Fly   146 LVSHKIEDYRNVEKVKEVLRTSIMSKQYGQ------EDFLNDLVSKACVSILPDEGTFNVDNIRI 204
            :......|..|.|.:.:...|::.||...:      |..:|.:::.|      |....:|| ..:
Zfish   151 IGDSFPVDPNNTESLVQTAMTTLGSKVINRCHRQMAEIAVNAILTVA------DMERKDVD-FEL 208

  Fly   205 CKI---LGSGLTKSEVVRGMVF-KRFVEGDVTYAEK-AKIVIFSCPVDIIQTETKGTVLIKSADE 264
            .|:   :|..|..:::::|::. |.|....:....| .||.|.:||.:..:.:||..:.:.|.::
Zfish   209 IKVEGKVGGKLEDTQLIKGVIVDKEFSHPQMPKVLKDTKIAILTCPFEPPKPKTKHKLDVTSVED 273

  Fly   265 LLSFSSGEESLLESQIKAIADAGVKVVVAGGKVGDMALHFLNKYGLMAVRLNSKFDLRRLSRSVN 329
            ..:....|:...:..|:.:.:.|..:.:......|.|.|.|.:..|.|:|.....::..::.:..
Zfish   274 YKALQKYEKDKFQEMIRQVKENGANLAICQWGFDDEANHLLLQNELPAIRWVGGPEIELIAIATG 338

  Fly   330 ATVLPRITTPSQEEL---GYCDKVCIEELGDTTIVAFRNEGKDSRIATVVIRGATDNFMDDIERA 391
            ..::||....:.|:|   |...::|.....|..:|.  .|.|:||..|:.|||.....:::.:||
Zfish   339 GRIVPRFCELTPEKLGTAGLVKEICFGTTKDRMLVI--EECKNSRAVTIFIRGGNKMIIEEAKRA 401

  Fly   392 LDDAINNFKCLTRDGRYLPGAGATEIELATQLSAYADTLPGLDQYAVRKFANALEVFPKALAENS 456
            |.||:...:.|.||.|.:.|.||:||..|..::..||..|.|:|||:|.||:||||.|.||||||
Zfish   402 LHDALCVIRNLVRDNRIVYGGGASEIACALAVNEAADKCPSLEQYAMRAFADALEVIPMALAENS 466

  Fly   457 GINGTEIVNQLYLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKFWGLKYAVGAAATILK 521
            |:|..:.:.::......|....:|  |:....||.|..:..:.:....|...:..|......|||
Zfish   467 GLNPIQTMTEVRARQVKENNSALG--IDCLHLSTNDMKQQHVIETLIGKKQQISLATQVVKMILK 529

  Fly   522 VDQI 525
            :|.|
Zfish   530 IDDI 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	164/520 (32%)
CCT8	NP_610418.1	Cpn60_TCP1	40..529	CDD:278544	157/500 (31%)
cct5	NP_997778.1	TCP1_epsilon	10..535	CDD:239455	165/524 (31%)
cct5	NP_997778.1	Cpn60_TCP1	44..533	CDD:278544	156/499 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920