Protein Alignment CCT8 and Cct5

DIOPT Version :10

• Sequence 1: NP_610418.1
• Gene: CCT8 / 35882
• FlyBaseID: FBgn0284436
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_031663.1
• Gene: Cct5 / 12465
• MGIID: 107185
• Length: 541
• Species: Mus musculus
• Alignment Length: 539
• Identity: 170/539 - (31%)
• Similarity: 274/539 - (50%)
• Gaps: 50/539 - (9%)

  Fly    14 MLKDGAR--MYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVTSDAGTIMREL 76
            ::||..|  ...|| ||:..:|.|.|..|.|||::.||||::||:::......:|:|..||:..:
Mouse    18 IIKDQDRKSRLMGL-EALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGATILSMM 81

  Fly    77 DVEHPAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAEISDGYEKALEKALE 141
            ||:|..|||:|..|:.||.|:||||..||||||||||.||:||..||....|:||||:|...|::
Mouse    82 DVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQ 146

  Fly   142 ILPNLVSHKIEDYRNVEKVKEVLRTSIMSKQYGQEDFLNDLVSKAC-----------VSILPDEG 195
            .|..:....:.|..|.|.:.:..:|::.||           |..:|           |..:.|..
Mouse   147 HLDKISDKVLVDINNPEPLIQTAKTTLGSK-----------VINSCHRQMAEIAVNAVLTVADME 200

  Fly   196 TFNVDNIRICKI---LGSGLTKSEVVRGMVFKRFVEGDVTYAE------KAKIVIFSCPVDIIQT 251
            ..:|| ..:.|:   :|..|..:::::|::    |:.|.::.:      .|||.|.:||.:..:.
Mouse   201 RRDVD-FELIKVEGKVGGRLEDTKLIKGVI----VDKDFSHPQMPKKVVDAKIAILTCPFEPPKP 260

  Fly   252 ETKGTVLIKSADELLSFSSGEESLLESQIKAIADAGVKVVVAGGKVGDMALHFLNKYGLMAVRLN 316
            :||..:.:.|.::..:....|:...|..||.|.:.|..:.:......|.|.|.|.:.||.|||..
Mouse   261 KTKHKLDVMSVEDYKALQKYEKEKFEEMIKQIKETGANLAICQWGFDDEANHLLLQNGLPAVRWV 325

  Fly   317 SKFDLRRLSRSVNATVLPRITTPSQEELGYCDKVCIEELG-----DTTIVAFRNEGKDSRIATVV 376
            ...::..::.:....::||.:..:.|:||:..  .::|:.     |..:|.  .:.|:||..|:.
Mouse   326 GGPEIELIAIATGGRIVPRFSELTSEKLGFAG--VVQEISFGTTKDKMLVI--EKCKNSRAVTIF 386

  Fly   377 IRGATDNFMDDIERALDDAINNFKCLTRDGRYLPGAGATEIELATQLSAYADTLPGLDQYAVRKF 441
            |||.....:::.:|:|.||:...:.|.||.|.:.|.||.||..|..:|..||..|.|:|||:|.|
Mouse   387 IRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAF 451

  Fly   442 ANALEVFPKALAENSGINGTEIVNQLYLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKF 506
            |:||||.|.||:||||:|..:.:.::......|:...:|.|. ..|.|. |.....:.:....|.
Mouse   452 ADALEVIPMALSENSGMNPIQTMTEVRARQVKESNPALGIDC-LHKGSN-DMQYQHVIETLIGKK 514

  Fly   507 WGLKYAVGAAATILKVDQI 525
            ..:..|......|||:|.|
Mouse   515 QQISLATQMVRMILKIDDI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	168/533 (32%)
Cct5	NP_031663.1	TCP1_epsilon	10..535	CDD:239455	170/539 (32%)