Protein Alignment CCT8 and Cct3

DIOPT Version :10

• Sequence 1: NP_610418.1
• Gene: CCT8 / 35882
• FlyBaseID: FBgn0284436
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_033966.1
• Gene: Cct3 / 12462
• MGIID: 104708
• Length: 545
• Species: Mus musculus
• Alignment Length: 554
• Identity: 151/554 - (27%)
• Similarity: 269/554 - (48%)
• Gaps: 43/554 - (7%)

  Fly    11 VSQMLK--DGARMYSGLEEAVFRNISACKEFAQTMRSAYGPNGMNKMIINHIEKQFVTSDAGTIM 73
            :||..|  .|.::.||       ||:|.|..|..:|:..||..|.||:::.:....:|:|...|:
Mouse    10 LSQNTKRESGRKVQSG-------NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAIL 67

  Fly    74 RELDVEHPAAKLIVMASQMQDAEVGDGTNFVVVLAGALLESAEELLRLGITTAEISDGYEKALEK 138
            ||:.|:|||||.::..|:.||.||||||..|::|||.:|..||..|...:....:...|..||:.
Mouse    68 REIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRMALDD 132

  Fly   139 ALEILPNLVSHKIEDYRNVEKVKEVLRTSIMSKQYGQEDFLNDLVSKACVSIL--------PDEG 195
            .:..|.. :|..: |..|.|.:..::.:||.:|      .::...|.||...|        .:.|
Mouse   133 MISTLKK-ISTPV-DVNNREMMLSIINSSITTK------VISRWSSLACNIALDAVKTVQFEENG 189

  Fly   196 TFNVD---NIRICKILGSGLTKSEVVRGMVFKRFVEGDVT------YAEKAKIVIFSCPVDIIQT 251
            ...:|   ..|:.||.|..:..|.|:||::..:    |||      |.:..:||:....::..:.
Mouse   190 RKEIDIKKYARVEKIPGGIIEDSCVLRGVMINK----DVTHPRMRRYIKNPRIVLLDSSLEYKKG 250

  Fly   252 ETKGTVLIKSADELLSFSSGEESLLESQIKAIADAGVKVVVAGGKVGDMALHFLNKYGLMAVRLN 316
            |::..:.|...::.......||..:....:.|......||:....:.|:|.|:|.:..:.|:|..
Mouse   251 ESQTDIEITREEDFTRILQMEEEYIHQLCEDIIQLKPDVVITEKGISDLAQHYLMRANVTAIRRV 315

  Fly   317 SKFDLRRLSRSVNATVLPRITTPSQEELGY-CDKVCIEELGDTTIVAFRNEGKDSRIATVVIRGA 380
            .|.|..|::|:..|.::.|.....::::|. ...:.|:::|| ....|..:.||.:..|:::|||
Mouse   316 RKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD-EYFTFITDCKDPKACTILLRGA 379

  Fly   381 TDNFMDDIERALDDAINNFKCLTRDGRYLPGAGATEIELATQLSAYADTLPGLDQYAVRKFANAL 445
            :...:.::||.|.||:...:.:..|.:.:||.||:|:.:|..|:..:..:.|::|:..|..|.||
Mouse   380 SKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQAL 444

  Fly   446 EVFPKALAENSGINGTEIVNQLYLAHNNEAGKTIGFDIEAEKASTIDTTKAKLFDLYQSKFWGLK 510
            ||.|:.|.:|.|.:...::..|...|..|:.:|.|  :..|..:.:|..:..:::....|....|
Mouse   445 EVIPRTLIQNCGASTIRLLTSLRAKHTQESCETWG--VNGETGTLVDMKELGIWEPLAVKLQTYK 507

  Fly   511 YAVGAAATILKVDQIIMA-KRAGGPKVRQAAGSD 543
            .||..|..:|::|.|:.. |:.|..:.||....|
Mouse   508 TAVETAVLLLRIDDIVSGHKKKGDDQNRQTGAPD 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT8	NP_610418.1	TCP1_theta	20..529	CDD:239457	142/527 (27%)
Cct3	NP_033966.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		4/13 (31%)
		chap_CCT_gamma	6..529	CDD:274085	147/540 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545		5/16 (31%)