DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MrgBP and EAF7

DIOPT Version :9

Sequence 1:	NP_610417.1	Gene:	MrgBP / 35880	FlyBaseID:	FBgn0033341	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_014263.1	Gene:	EAF7 / 855586	SGDID:	S000005080	Length:	425	Species:	Saccharomyces cerevisiae

Alignment Length:	248	Identity:	57/248 - (22%)
Similarity:	93/248 - (37%)	Gaps:	80/248 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 WSAEEELQLFHAMEGLRPVGINKHFYMSCIVQRLSK--------------SLNREMPSELIWRHL 75
            |:..:|::|.......:|.||:|||:|.|||:|::.              .|.:...::.||..|
Yeast     5 WTIVDEIRLLRWASEFKPAGIHKHFHMFCIVERMNSPDKYPVTLLQKETMKLGKVFTAKDIWDKL 69

  Fly    76 GTMYKLKELDDLE---SLPFPNE-----------------------------EREFSLPEQDYGT 108
            ...|.|:::|::|   ||....|                             :::|:||.::||.
Yeast    70 SQSYNLEKIDEMENTYSLEATTESSRNGNGNGDDAEIHEETLLELNNRIRVRKQDFTLPWEEYGE 134

  Fly   109 L---QTKKTVEVHANEEAAEAQSAPPTAETNGKAPPATKTPVPTNSTKDGDKKPVAKPQEQLP-- 168
            |   ..:|:  .::|||....:.......|..|..|:|..   .|.....:|....|.:| ||
Yeast   135 LILENARKS--PNSNEEYPRVEDMNEKDSTIPKESPSTDL---KNDNNKQEKNATIKVKE-LPEY 193

  Fly   169 ------------KRPAKRT--------RGSMSNES---ISPSTTPPPVQSNKR 198
                        |.|.|..        |..||.|.   .|.:.|..||:.::|
Yeast   194 HTEENDSPIDVQKEPIKEVQSDEKELQREHMSEEEQKMKSTNKTAAPVRKSQR 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MrgBP	NP_610417.1	Eaf7	29..106	CDD:285187	27/122 (22%)
EAF7	NP_014263.1	Eaf7	9..132	CDD:400315	27/122 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I3193
eggNOG	1	0.900	-	-		E1_KOG4051
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005866
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105343
Panther	1	1.100	-	-	LDO	PTHR13581
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5107
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890