DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MrgBP and Mrgbp

DIOPT Version :9

Sequence 1:	NP_610417.1	Gene:	MrgBP / 35880	FlyBaseID:	FBgn0033341	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_082755.1	Gene:	Mrgbp / 73247	MGIID:	1920497	Length:	204	Species:	Mus musculus

Alignment Length:	204	Identity:	73/204 - (35%)
Similarity:	108/204 - (52%)	Gaps:	22/204 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DKGLAVAGTAAPLPAALDHEWSAEEELQLFHAMEGLRPVGINKHFYMSCIVQRLSKSLNREMPSE 69
            |||   .|.|||.||.....||.|.|:.|||||.|.:|||:|:||:|.||..:.|:::.|::||:
Mouse    14 DKG---PGEAAPSPAEETVVWSPEVEVCLFHAMLGHKPVGVNRHFHMICIRDKFSQNIGRQVPSK 75

  Fly    70 LIWRHLGTMYKLKELDDLESLPFPNEEREFSLPEQDYGTLQTKKTV-EVHANEEAAE-------A 126
            :||.||.|||.::.|.:.|.|||||.||.|.||::....::..|.| |....||..|       |
Mouse    76 VIWDHLSTMYDMQALHESEILPFPNPERNFVLPDEIIQEVREGKVVIEEEMKEEMKEDVDPHSGA 140

  Fly   127 QSAPPTAETNGKAPPATKTPVPTNSTKDGDKKPVAKPQEQLPKRPAKRTRGSMSNESISPSTTPP 191
            .....::.:.|||...:......||:..|.|:..           .||.|..::::.::.::.|.
Mouse   141 DDVFSSSGSLGKALEKSSKDKEKNSSDLGCKEGA-----------DKRKRSRVTDKVLTANSNPS 194

  Fly   192 PVQSNKRRR 200
            ...:.||||
Mouse   195 SPSAAKRRR 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MrgBP	NP_610417.1	Eaf7	29..106	CDD:285187	39/76 (51%)
Mrgbp	NP_082755.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		9/15 (60%)
		Eaf7	36..>94	CDD:400315	28/57 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..204		19/87 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846154
Domainoid	1	1.000	71	1.000	Domainoid score	I9437
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10104
Inparanoid	1	1.050	114	1.000	Inparanoid score	I4827
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005866
OrthoInspector	1	1.000	-	-		oto95076
orthoMCL	1	0.900	-	-		OOG6_105343
Panther	1	1.100	-	-	LDO	PTHR13581
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5633
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.850