Protein Alignment CG8272 and AMN1

DIOPT Version :9

• Sequence 1: NP_001260812.1
• Gene: CG8272 / 35875
• FlyBaseID: FBgn0033337
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_009716.1
• Gene: AMN1 / 852455
• SGDID: S000000362
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 409
• Identity: 79/409 - (19%)
• Similarity: 131/409 - (32%)
• Gaps: 151/409 - (36%)

  Fly   410 NGATDEAIQSVIGQLRWL--RELSLEHCSGLTDAALTGI---NISKLEMSRKQSGSQVSSMDNFY 469
            |.||:.|         |.  |.:|....|.:|...:..|   ..|:|::.:..:.....|...|.
Yeast   113 NTATENA---------WATSRVVSASSLSIVTPTEIKNILVDEFSELKLGQPLTAQHQRSHAVFE 168

  Fly   470 PP--------------YSNTLAERDSLAGSLQSIKISLRSKAEDEIVRDARRKQAMLAAYEMNLI 520
            .|              .:|...||..|..:.||.:.||....::|     |.|:|..||.:   :
Yeast   169 IPEIVENIIKMIVSLESANIPKERPCLRRNPQSYEHSLLMYKDEE-----RAKKAWSAAQQ---L 225

  Fly   521 REDDFEGH-------------------NIQQLRGLRSLNLRGCNKISDV---------------S 551
            |:....||                   |:.:....:||:.:..:...:.               .
Yeast   226 RDPPLVGHKEKKQGALFSCMMVNRLWLNVTRPFLFKSLHFKSVHNFKEFLRTSQETTQVMRPSHF 290

  Fly   552 LKYGLKHI---ELRRLMLSNCQQISLLGMEAMASSCPSI-------------EELDLSDCYNITD 600
            :.:.|..:   ::.||....||.:..|....    ||.|             |:|.:....||.|
Yeast   291 ILHKLHQVTQPDIERLSRMECQNLKWLEFYV----CPRITPPLSWFDNLHKLEKLIIPGNKNIDD 351

  Fly   601 KTIQVVTSKLPRLKALHISGCSQLTEHTLDAIITNCSCLQTLSIYRCR-------------SMYT 652
            ..:..::..:|.||.|.:..|..:::..:..|..||..|:|.:|.|.|             ..||
Yeast   352 NFLLRLSQSIPNLKHLVLRACDNVSDSGVVCIALNCPKLKTFNIGRHRRGNLITSVSLVALGKYT 416

  Fly   653 DLE-------------------------ERLS----------------GVKTLRNL------NMD 670
            .:|                         ||||                .:.:..||      |:|
Yeast   417 QVETVGFAGCDVDDAGIWEFARLNGKNVERLSLNSCRLLTDYSLPILFALNSFPNLAVLEIRNLD 481

  Fly   671 NLTSIDNAEFFRL-KKRLD 688
            .:|.:.:...:.| ||.||
Yeast   482 KITDVRHFVKYNLWKKSLD 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8272	NP_001260812.1	AMN1	269..440	CDD:187754	8/31 (26%)
		leucine-rich repeat	270..295	CDD:275381
		leucine-rich repeat	296..319	CDD:275381
		leucine-rich repeat	322..346	CDD:275381
		leucine-rich repeat	347..399	CDD:275381
		leucine-rich repeat	400..426	CDD:275381	4/15 (27%)
		leucine-rich repeat	427..535	CDD:275381	28/145 (19%)
		AMN1	515..>642	CDD:187754	29/176 (16%)
		leucine-rich repeat	536..560	CDD:275381	3/41 (7%)
		leucine-rich repeat	561..586	CDD:275381	6/24 (25%)
		leucine-rich repeat	587..612	CDD:275381	6/37 (16%)
		leucine-rich repeat	613..638	CDD:275381	7/24 (29%)
		leucine-rich repeat	639..663	CDD:275381	12/77 (16%)
		F-box-like	12..>44	CDD:289689
		leucine-rich repeat	129..166	CDD:275381
		leucine-rich repeat	167..192	CDD:275381
		leucine-rich repeat	193..244	CDD:275381
		C2	<231..274	CDD:301316
		leucine-rich repeat	246..269	CDD:275381
AMN1	NP_009716.1	AMN1	285..509	CDD:187754	44/220 (20%)
		leucine-rich repeat	314..337	CDD:275381	4/26 (15%)
		leucine-rich repeat	338..363	CDD:275381	5/24 (21%)
		leucine-rich repeat	364..389	CDD:275381	7/24 (29%)
		leucine-rich repeat	390..417	CDD:275381	6/26 (23%)
		leucine-rich repeat	418..443	CDD:275381	1/24 (4%)
		leucine-rich repeat	444..471	CDD:275381	4/26 (15%)
		leucine-rich repeat	472..493	CDD:275381	4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900