DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8272 and fbxl17

DIOPT Version :9

Sequence 1:	NP_001260812.1	Gene:	CG8272 / 35875	FlyBaseID:	FBgn0033337	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_001335097.5	Gene:	fbxl17 / 795023	ZFINID:	ZDB-GENE-111013-3	Length:	409	Species:	Danio rerio

Alignment Length:	267	Identity:	49/267 - (18%)
Similarity:	101/267 - (37%)	Gaps:	49/267 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   447 NISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAG---SLQSIKISLRSKAEDEI------- 501
            :|..|..|...|.|..|..|       ...|.|.|..|   :..|.....:::|.:||
Zfish   160 SICPLPSSSSSSSSSASEED-------GATAGRHSDPGGATTCSSSSCCCQTEASEEIKSTENTD 217

  Fly   502 --------------------VRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRGCNK 546
                                |::.....:::..|..:|..:..|          .:.::|.|..:
Zfish   218 TSHINQLPSSILLKVFSHLSVKERCLAASLVCKYWRDLCLDFQF----------WKQIDLSGLQQ 272

  Fly   547 I-SDVSLKYGLKHIELRRLMLSNCQQISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVVTSKL 610
            : .|:.:|...:...:..:.:|:|:.:...|:.|:||:|..:.:.....|..::|.::..|....
Zfish   273 VKDDLLVKIASRRQNVTEINISDCRNVQDHGVCALASNCAGLIKYTAYRCKQLSDVSLSTVAIHC 337

  Fly   611 PRLKALHISGCSQLTEHTLDAIITNCSCLQTLSIYRCRSMYTD-LEERLSGVKTLRNLNMDNLTS 674
            |.|:.:|:....:||:|.|..:..:|..|:.:...:|.|:..: |.....|...|:.:.|.....
Zfish   338 PLLQKVHVGNQDKLTDHALKLLGDHCKELKDVHFGQCYSISDEGLMSLAQGCNKLQRIYMQENKL 402

  Fly   675 IDNAEFF 681
            :..|..:
Zfish   403 VSQAGIY 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8272	NP_001260812.1	AMN1	269..440	CDD:187754
		leucine-rich repeat	270..295	CDD:275381
		leucine-rich repeat	296..319	CDD:275381
		leucine-rich repeat	322..346	CDD:275381
		leucine-rich repeat	347..399	CDD:275381
		leucine-rich repeat	400..426	CDD:275381
		leucine-rich repeat	427..535	CDD:275381	19/117 (16%)
		AMN1	515..>642	CDD:187754	26/127 (20%)
		leucine-rich repeat	536..560	CDD:275381	4/24 (17%)
		leucine-rich repeat	561..586	CDD:275381	7/24 (29%)
		leucine-rich repeat	587..612	CDD:275381	3/24 (13%)
		leucine-rich repeat	613..638	CDD:275381	7/24 (29%)
		leucine-rich repeat	639..663	CDD:275381	5/24 (21%)
		F-box-like	12..>44	CDD:289689
		leucine-rich repeat	129..166	CDD:275381
		leucine-rich repeat	167..192	CDD:275381
		leucine-rich repeat	193..244	CDD:275381
		C2	<231..274	CDD:301316
		leucine-rich repeat	246..269	CDD:275381
fbxl17	XP_001335097.5	F-box-like	221..268	CDD:289689	4/56 (7%)
		AMN1	257..>397	CDD:187754	29/149 (19%)
		leucine-rich repeat	262..287	CDD:275381	4/24 (17%)
		leucine-rich repeat	288..313	CDD:275381	7/24 (29%)
		leucine-rich repeat	314..339	CDD:275381	3/24 (13%)
		leucine-rich repeat	340..365	CDD:275381	7/24 (29%)
		leucine-rich repeat	366..391	CDD:275381	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588030
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740