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Protein Alignment CG8272 and FBXL15

DIOPT Version :9

Sequence 1:	NP_001260812.1	Gene:	CG8272 / 35875	FlyBaseID:	FBgn0033337	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	XP_005270206.1	Gene:	FBXL15 / 79176	HGNCID:	28155	Length:	387	Species:	Homo sapiens

Alignment Length:	278	Identity:	64/278 - (23%)
Similarity:	110/278 - (39%)	Gaps:	73/278 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   425 RWLRELSLEHCSGLT--DAALTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAGSLQ 487
            |..|.|...|.:||.  |||..|..|.:..::|
Human   136 RAFRSLVQLHLAGLRRFDAAQVGPQIPRAALAR-------------------------------- 168

  Fly   488 SIKISLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFE---GHNIQQLRGLRSLNLRGCNKISD 549
                         ::|||...|.:..|.....:.::|..   ..|.|    |||:.|.||.::|.
Human   169 -------------LLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQ----LRSVALGGCGQLSR 216

  Fly   550 ---VSLKYGLKHIELRRLMLSNCQQISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVVTSKL- 610
               .:|..|..  .|:||.|::|..:..|.:..:|..||::|||||:.|..:.|:.|..:..:.
Human   217 RALGALAEGCP--RLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRG 279

  Fly   611 PRLKALHISGCSQLTEHTLDAIITNCSCLQTLSIYRCRSMYTDLEERLSGVKT-------LRNLN 668
            ..|::|.::..:.:.:..:..:..||..|..|.:..|..:.:|      ||:|       ||:|.
Human   280 AGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD------GVRTLAEYCPVLRSLR 338

  Fly   669 MDNLTSIDNAEFFRLKKR 686
            :.:...:..:...||:||
Human   339 VRHCHHVAESSLSRLRKR 356

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.