DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8272 and fbxl7

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_001073511.1 Gene:fbxl7 / 569430 ZFINID:ZDB-GENE-061215-122 Length:489 Species:Danio rerio


Alignment Length:418 Identity:90/418 - (21%)
Similarity:162/418 - (38%) Gaps:135/418 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   244 RTLRVLNFSHTLIGQALLALC----DLNLQLQRLYLAGCRQLNCTTILNFLATQPQLCALDLSAT 304
            |.||||.          ..||    ::.|.::.:.::|||:|                       
Zfish   166 RALRVLT----------RRLCQDTPNVCLTVETVMVSGCRRL----------------------- 197

  Fly   305 MCVNDENLAALVQTNPQLEHLKVNGCLSITNAGAIHLAKLKC--LKSLDISNCDNLTSSGIIEGI 367
               .|..|..:.|:.|:|..|:|.||.:::|.....:.. :|  |:.||:|.|..:|...:...:
Zfish   198 ---TDRGLYTVAQSCPELRRLEVAGCYNVSNEAVFEVVS-RCPNLEHLDVSGCSKVTCISLTRDV 258

  Fly   368 ASEENPVI-QELNVSYLQI--C----EECIKAIASNLRCLRSLHLNHCVNGATDEAIQSVIGQLR 425
            :.:.:|:. |::::.:|.:  |    :|.:..||::...|..|:|..||. .|||.::.::....
Zfish   259 SVKLSPLHGQQISIRFLDMTDCFALEDEGLHTIAAHCTQLTHLYLRRCVR-LTDEGLRFLVIYCP 322

  Fly   426 WLRELSLEHCSGLTDAALTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAGSLQSIK 490
            .:||||:..|..::|..|.  .|:||                                       
Zfish   323 GVRELSVSDCRFISDFGLR--EIAKL--------------------------------------- 346

  Fly   491 ISLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRGCNKISDVSLKYG 555
                                               ||.       ||.|::..|::|:||.::|.
Zfish   347 -----------------------------------EGR-------LRYLSIAHCSRITDVGVRYV 369

  Fly   556 LKHI-ELRRLMLSNCQQISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVVTSKLPRLKALHIS 619
            .|:. .||.|....|:.::..|:|.:|.||..::.||:..|..::|..::.:......||.|.:.
Zfish   370 AKYCSRLRYLNARGCEGLTDHGIEHLAKSCLKLKSLDIGKCPLVSDAGLEQLALNSFNLKRLSLK 434

  Fly   620 GCSQLTEHTLDAIITNCSCLQTLSIYRC 647
            .|..:|...|..:..||..||.|::..|
Zfish   435 SCESITGRGLQVVAANCFDLQLLNVQDC 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 41/179 (23%)
leucine-rich repeat 270..295 CDD:275381 4/24 (17%)
leucine-rich repeat 296..319 CDD:275381 3/22 (14%)
leucine-rich repeat 322..346 CDD:275381 6/23 (26%)
leucine-rich repeat 347..399 CDD:275381 13/58 (22%)
leucine-rich repeat 400..426 CDD:275381 8/25 (32%)
leucine-rich repeat 427..535 CDD:275381 12/107 (11%)
AMN1 515..>642 CDD:187754 34/127 (27%)
leucine-rich repeat 536..560 CDD:275381 9/24 (38%)
leucine-rich repeat 561..586 CDD:275381 9/24 (38%)
leucine-rich repeat 587..612 CDD:275381 4/24 (17%)
leucine-rich repeat 613..638 CDD:275381 8/24 (33%)
leucine-rich repeat 639..663 CDD:275381 4/9 (44%)
F-box-like 12..>44 CDD:289689
leucine-rich repeat 129..166 CDD:275381
leucine-rich repeat 167..192 CDD:275381
leucine-rich repeat 193..244 CDD:275381 90/418 (22%)
C2 <231..274 CDD:301316 8/33 (24%)
leucine-rich repeat 246..269 CDD:275381 6/26 (23%)
fbxl7NP_001073511.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..76
F-box-like 112..158 CDD:289689
leucine-rich repeat 127..151 CDD:275381
leucine-rich repeat 152..185 CDD:275381 7/28 (25%)
LRR 1 168..193 7/34 (21%)
AMN1 <183..364 CDD:187754 54/291 (19%)
leucine-rich repeat 186..211 CDD:275381 7/50 (14%)
LRR 2 194..219 10/50 (20%)
leucine-rich repeat 212..233 CDD:275381 6/20 (30%)
LRR 3 220..245 6/25 (24%)
leucine-rich repeat 238..271 CDD:275381 8/32 (25%)
LRR 4 251..279 3/27 (11%)
leucine-rich repeat 272..297 CDD:275381 5/24 (21%)
LRR 5 280..305 7/24 (29%)
AMN1 295..463 CDD:187754 54/252 (21%)
leucine-rich repeat 298..323 CDD:275381 8/25 (32%)
LRR 6 306..331 9/25 (36%)
leucine-rich repeat 324..349 CDD:275381 11/100 (11%)
LRR 7 332..357 11/107 (10%)
leucine-rich repeat 350..375 CDD:275381 9/24 (38%)
LRR 8 358..383 9/24 (38%)
leucine-rich repeat 376..401 CDD:275381 9/24 (38%)
LRR 9 384..409 8/24 (33%)
leucine-rich repeat 402..427 CDD:275381 4/24 (17%)
LRR 10 410..435 5/24 (21%)
leucine-rich repeat 428..451 CDD:275381 6/22 (27%)
LRR 11 436..461 8/24 (33%)
leucine-rich repeat 454..478 CDD:275381 4/9 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170588048
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.740

Return to query results.
Submit another query.