Protein Alignment CG8272 and LOC4577562

DIOPT Version :10

• Sequence 1: NP_001260812.1
• Gene: CG8272 / 35875
• FlyBaseID: FBgn0033337
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: XP_001238345.2
• Gene: LOC4577562 / 4577562
• VectorBaseID: AGAMI1_013227
• Length: 646
• Species: Anopheles gambiae
• Alignment Length: 673
• Identity: 171/673 - (25%)
• Similarity: 299/673 - (44%)
• Gaps: 119/673 - (17%)

  Fly    11 YDDLPLEIVLKIFSYLGYSDLQAAGSTCQRWHAALDQAEFNQRTRVCFSKVVLSDQLSPGVDLMR 75
            :|:||:||:|.||.:|...|..||..||:||..|:...||.......|.:|.:.|...|....:|
Mosquito    74 FDNLPMEILLNIFRFLNGVDRDAAALTCKRWFDAMGYREFLDEVCFHFEEVSICDGTPPIALFLR 138

  Fly    76 CERRFQHFLFEDVTLGQVKELMRFMGRTAQSLALDN-VDLNDKQFYGMLGVLPHLHSLSLKRCLP 139
            ..|.|.:.....|......|.....|...:.:...| :.|...:...:|..||.|..|:|:....
Mosquito   139 SFRHFSNIKLTRVQFNGYCEFWDVFGEYLREITFCNCITLTKSKLTMILKRLPFLECLALEEADE 203

  Fly   140 LFMSGSFLDSYNNSCPDLNDLASNLAGIKELTLCENQYLTDAILMRLTSFMPSLEAINMSGCHIA 204
            .|.:.:.:        :|..:......:::|.|.::...|...|..|.:..|::.|:.:|.|
Mosquito   204 FFKTWTPV--------ELKRIEPVCRCLRKLALRKSNAFTVDHLYYLVAMGPNISALEISKC--- 257

  Fly   205 FHNAIHRRFYPATSSSDHVLPSE-SVLTFKFILTILNLQRRTLRVLNFSHTLIGQALL-ALCDL- 266
                        ....|  .|:. .:||  .||||:.::::.|:.::||:|:.....| ...::
Mosquito   258 ------------LKQID--APTRVKILT--TILTIMKMRKKKLQAVDFSYTMYDDLFLKQFAEIE 306

  Fly   267 NLQLQRLYLAGCRQ--LNCTTILNFLATQPQLCALDLSATMCVNDENLAALVQTNPQLEHLKVNG 329
            |:.|.::.|:...:  :....|::.|..|..:..||||:.:.:.|..|..:..:...|:.||:||
Mosquito   307 NMSLSQISLSFFERAPIKDPGIIDILRCQSAIVHLDLSSFLNLTDFALIEISTSLRLLKTLKLNG 371

  Fly   330 CLSITNAGAIHLAKLKCLKSLDISNCDNLTSSGIIEGIASEENPVIQELNVSYLQ-ICEECIKAI 393
            |..:|:.|...:.||..|:.||:|:||.::..|.::.|.......:.:|.:|.|. :.:..|..|
Mosquito   372 CWLLTDFGVESIYKLDRLQVLDLSDCDKISDRGFMKAIVDRRRDCMSQLYLSMLPGLTDSVILKI 436

  Fly   394 ASNLRCLRSLHL-------NHCVNGATDEAIQSVIGQLRWLRELSLEHCSGLTDAALTGIN--IS 449
                 ||..|:|       :.|:|   |.::|.:...|:.||.|.|..|..::||.|||.|  ::
Mosquito   437 -----CLTLLNLTVIDFCGSDCMN---DTSVQFLFCYLKCLRILRLNGCVKISDAGLTGENLPVA 493

  Fly   450 KLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAGSLQSIKISLRSKAEDEIVRDARRKQAMLAA 514
            .:|:...|:                |.|
Mosquito   494 VIEIWDTQT----------------TFA------------------------------------- 505

  Fly   515 YEMNLIREDDFEGHNIQQLRGLRSLNLRGCNKISDVSLKYGLKHIELRRLMLSNCQQISLLGMEA 579
                           |.:||.|:.|.|.||.|::|.:|.:..:..|||.|.|::|.|||..|:||
Mosquito   506 ---------------ICELRSLQELQLSGCFKVTDFTLTHAFRFRELRELNLAHCVQISEPGIEA 555

  Fly   580 MASSCPSIEELDLSDCYNITDKTIQVVTSKLPRLKALHISGCSQLTEHTLDAIITNCSCLQTLSI 644
            |:.:||::|::|:|||:::.|:.:..:...|.||::|.:.....||..::||::.....|:.::|
Mosquito   556 MSLNCPALEQIDMSDCFHVNDRCVVAMAKNLVRLRSLKLVRLPLLTVTSVDALVEYAKALRYINI 620

  Fly   645 YRCRSMYTDLEERLSGVKTLRNL 667
            ..|..:..|..|||..:.||||:
Mosquito   621 RGCPKIPKDAPERLKKIATLRNI 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8272	NP_001260812.1	F-box_SF	11..58	CDD:459239	19/46 (41%)
		leucine-rich repeat	129..166	CDD:275381	5/36 (14%)
		leucine-rich repeat	167..192	CDD:275381	5/24 (21%)
		leucine-rich repeat	193..244	CDD:275381	11/51 (22%)
		C2	<231..274	CDD:472691	12/44 (27%)
		leucine-rich repeat	246..269	CDD:275381	6/24 (25%)
		AMN1	269..440	CDD:187754	48/180 (27%)
		leucine-rich repeat	270..295	CDD:275381	5/26 (19%)
		leucine-rich repeat	296..319	CDD:275381	6/22 (27%)
		leucine-rich repeat	322..346	CDD:275381	10/23 (43%)
		leucine-rich repeat	347..399	CDD:275381	13/52 (25%)
		leucine-rich repeat	400..426	CDD:275381	8/32 (25%)
		leucine-rich repeat	427..535	CDD:275381	17/109 (16%)
		AMN1	515..>642	CDD:187754	41/126 (33%)
		leucine-rich repeat	536..560	CDD:275381	8/23 (35%)
		leucine-rich repeat	561..586	CDD:275381	13/24 (54%)
		leucine-rich repeat	587..612	CDD:275381	7/24 (29%)
		leucine-rich repeat	613..638	CDD:275381	6/24 (25%)
		leucine-rich repeat	639..663	CDD:275381	7/23 (30%)
LOC4577562	XP_001238345.2	None