DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8272 and CG14891

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_650560.1 Gene:CG14891 / 42013 FlyBaseID:FBgn0038445 Length:495 Species:Drosophila melanogaster


Alignment Length:535 Identity:112/535 - (20%)
Similarity:195/535 - (36%) Gaps:158/535 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 IKELTLCENQYLTDAILMRLTSFMPSLEAIN-----MSGCHIAFHNAIH--------------RR 212
            :::||:..::......|::..|....:|.::     .|| .:.|:.|.|              ..
  Fly    26 VRQLTISGSRRFLKYQLLKYFSIFGKVEKLHWKKKKRSG-SVLFYEATHAAKALYCTKHTIDGHD 89

  Fly   213 FYPATSSSDHVLPSESVLTFKF------------ILTILNLQRRTLRVLNFSHTLIGQALLALCD 265
            .|...|:|.|..|.|...|...            :|..|:|..|    |||:         |.|:
  Fly    90 LYLQASTSWHPTPVEESGTLSAYDLPITDDIWWKVLDYLSLNER----LNFA---------ASCE 141

  Fly   266 ----------------LNLQ---------LQRLYLAGCRQLNCTTILNFLATQPQLCA-LDLSAT 304
                            ||::         ::||.|...:.::|.|........|.|.. :.|...
  Fly   142 RFQAIYELDSHRINHVLNMKDVCTLTHRVIKRLMLLSGKHIHCVTGGPLHPNWPYLTEFVQLLGV 206

  Fly   305 MCVNDENLAALVQTNPQLEHLK-----VNGCLSITN----------AGAIHLAKLKCLKSLDISN 354
            .|.|...| :..:.:..|.|:.     .||.::|||          |....|..|..||||||. 
  Fly   207 SCPNLTEL-SFFKISVSLAHMTHLFDGANGLINITNISLRRCNLKDAHIYCLQMLSKLKSLDIR- 269

  Fly   355 CDNLTSSGIIEGIASEENPV-IQELNVS-YLQICEECIKAIASNLRCLRSLHLNHCVNGATDEAI 417
             :|.:    |:|.:.:..|: ::.|||| .:.:..:|:..:|:         |:|          
  Fly   270 -ENFS----IKGDSLKSLPISLEILNVSGCVDLSPKCLIQLAA---------LSH---------- 310

  Fly   418 QSVIGQLRWLRELSLEHCSGLTDAALTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSL 482
                     ||||   .|.|:...|.......:|.               .|.|....|    .|
  Fly   311 ---------LREL---RCPGIVKFAKDNELYGRLA---------------HYCPMLEVL----EL 344

  Fly   483 AGSLQSIKISLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRGCNKI 547
            ...:..|::...|:....::..:    |.|..:..|::.....|.::::.|..|.|.........
  Fly   345 TDFMNVIQLGGLSRLHTLVIHSS----AQLDYHVNNVLLTSIAESYSLRHLEILDSFGPMSDTSF 405

  Fly   548 SDVSLKYGLKHIELRRLML--SNCQQISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVVTSKL 610
             |:|:...||  |||.|:|  .|...:.|:|::.::    ::|.||||...|::::.:..:|..|
  Fly   406 -DLSIFSQLK--ELRTLILHNQNFTTLHLMGLQKLS----TLEFLDLSGSPNLSNEVVAKLTKSL 463

  Fly   611 PRLKALHISGCSQLT 625
            ..|:.|.:..|..:|
  Fly   464 SGLRRLKVDFCPLIT 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 45/197 (23%)
leucine-rich repeat 270..295 CDD:275381 5/24 (21%)
leucine-rich repeat 296..319 CDD:275381 5/23 (22%)
leucine-rich repeat 322..346 CDD:275381 10/38 (26%)
leucine-rich repeat 347..399 CDD:275381 16/53 (30%)
leucine-rich repeat 400..426 CDD:275381 2/25 (8%)
leucine-rich repeat 427..535 CDD:275381 19/107 (18%)
AMN1 515..>642 CDD:187754 29/113 (26%)
leucine-rich repeat 536..560 CDD:275381 6/23 (26%)
leucine-rich repeat 561..586 CDD:275381 7/26 (27%)
leucine-rich repeat 587..612 CDD:275381 8/24 (33%)
leucine-rich repeat 613..638 CDD:275381 4/13 (31%)
leucine-rich repeat 639..663 CDD:275381
F-box-like 12..>44 CDD:289689
leucine-rich repeat 129..166 CDD:275381
leucine-rich repeat 167..192 CDD:275381 4/24 (17%)
leucine-rich repeat 193..244 CDD:275381 16/81 (20%)
C2 <231..274 CDD:301316 13/79 (16%)
leucine-rich repeat 246..269 CDD:275381 7/38 (18%)
CG14891NP_650560.1 RRM_6 25..91 CDD:290958 10/65 (15%)
AMN1 <199..352 CDD:187754 44/209 (21%)
leucine-rich repeat 211..237 CDD:275381 5/26 (19%)
leucine-rich repeat 239..262 CDD:275381 6/22 (27%)
leucine-rich repeat 263..285 CDD:275381 10/27 (37%)
leucine-rich repeat 286..338 CDD:275381 17/97 (18%)
leucine-rich repeat 339..387 CDD:275381 8/55 (15%)
leucine-rich repeat 388..415 CDD:275381 7/29 (24%)
leucine-rich repeat 416..439 CDD:275381 7/26 (27%)
leucine-rich repeat 440..465 CDD:275381 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457979
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR13318
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.930

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