DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8272 and fbxl3a

DIOPT Version :10

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_001005773.3 Gene:fbxl3a / 378451 ZFINID:ZDB-GENE-030912-5 Length:431 Species:Danio rerio


Alignment Length:475 Identity:88/475 - (18%)
Similarity:168/475 - (35%) Gaps:166/475 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   156 DLNDLASNLAGIKELTLCENQYLTDAILMRLTSFMPSLE-AINMSGCH---IAFH-NAIHRRF-- 213
            |..||.||..           .|...||:.:..::|.|: |.....||   .||| ..:.|.|  
Zfish    32 DFGDLQSNWV-----------RLPQEILLHIFQYLPLLDRAFASQVCHNWNHAFHMPELWRCFEF 85

  Fly   214 ---YPATSSSDHVLPSESVLTFKFILTILNLQRRTLRVLNFSHTLIGQALLALCDLNLQLQRLYL 275
               .||||......|.       .|..|:......|:.::|......::....||:..||     
Zfish    86 ELNQPATSYLKATHPD-------LIKQIIKRHSNHLQYVSFKVDSSTESAETACDILSQL----- 138

  Fly   276 AGCRQLNCT-TILNFLAT-QPQLCALDLS------ATMCVNDENLAAL-----VQTNPQLEHLKV 327
                 :||: ..|..::| :|....|..|      ..:.||.::|::|     ...:|.|:.|..
Zfish   139 -----VNCSLKTLGLISTARPSFMELPKSHFISALTVVFVNSKSLSSLKIDDTPVDDPSLKVLVA 198

  Fly   328 NGCLSITNAGAIHLAKLKCLKSLDISNCDNLTSSGIIEGIASEENPVIQELNVSYLQICEECIKA 392
            |..              ..||.|.:|:|.:::.:||:  ..:::...::||.::|..:.:|.:.|
Zfish   199 NNS--------------DTLKLLKMSSCPHVSPAGIL--CVADQCHGLRELALNYHLLSDELLLA 247

  Fly   393 IASNLRCLRSLHLNHCVNGATDEAIQSVIGQLRWLRELSLEHCSGLTDAALTGINISKLEMSRKQ 457
            ::|.    :.:||.|.                                         ::::..:.
Zfish   248 LSSE----KHVHLEHL-----------------------------------------RIDVVSEN 267

  Fly   458 SGSQVSSMDNFYPPYSNTLAERDSLAGSLQSIKISLRSKAEDEIVRDARRKQAMLAAYEMNLIRE 522
            .|.|      |:                      :::..:.|.:||.:.:...::..:    :.|
Zfish   268 PGQQ------FH----------------------TIKKSSWDAMVRHSPKFNLVMYFF----LYE 300

  Fly   523 DDFE--------------GHNI-QQLRGLRSLNLRGCNKISD-VSLKYGLKHI--ELRRLMLSNC 569
            |:|.              |.:: :::.|...:|   |.::.: |....||:.:  ||.|: ...|
Zfish   301 DEFGPFFRDEIPVTHLYFGRSVSKEVLGRVGMN---CPRLVELVVCANGLRPLDEELIRI-AERC 361

  Fly   570 QQISLLGMEAMASSCPSIEE 589
            |.:|.:|:.....||.:..|
Zfish   362 QFLSAIGLGECEVSCSAFVE 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 F-box_SF 11..58 CDD:459239
leucine-rich repeat 129..166 CDD:275381 5/9 (56%)
leucine-rich repeat 167..192 CDD:275381 3/24 (13%)
leucine-rich repeat 193..244 CDD:275381 16/60 (27%)
C2 <231..274 CDD:472691 8/42 (19%)
leucine-rich repeat 246..269 CDD:275381 4/22 (18%)
AMN1 269..440 CDD:187754 33/183 (18%)
leucine-rich repeat 270..295 CDD:275381 5/26 (19%)
leucine-rich repeat 296..319 CDD:275381 6/33 (18%)
leucine-rich repeat 322..346 CDD:275381 3/23 (13%)
leucine-rich repeat 347..399 CDD:275381 13/51 (25%)
leucine-rich repeat 400..426 CDD:275381 3/25 (12%)
leucine-rich repeat 427..535 CDD:275381 10/122 (8%)
AMN1 515..>642 CDD:187754 20/93 (22%)
leucine-rich repeat 536..560 CDD:275381 5/26 (19%)
leucine-rich repeat 561..586 CDD:275381 8/24 (33%)
leucine-rich repeat 587..612 CDD:275381 1/3 (33%)
leucine-rich repeat 613..638 CDD:275381
leucine-rich repeat 639..663 CDD:275381
fbxl3aNP_001005773.3 F-box_SF 39..80 CDD:459239 12/51 (24%)
FBXL3_LRR 83..431 CDD:467832 71/413 (17%)
leucine-rich repeat 178..203 CDD:275381 6/38 (16%)
leucine-rich repeat 204..229 CDD:275381 7/26 (27%)
leucine-rich repeat 230..255 CDD:275381 6/28 (21%)
leucine-rich repeat 256..291 CDD:275381 8/103 (8%)
leucine-rich repeat 292..336 CDD:275381 7/50 (14%)
leucine-rich repeat 337..363 CDD:275381 7/26 (27%)
leucine-rich repeat 364..389 CDD:275381 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

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