DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8272 and CG11044

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_611456.1 Gene:CG11044 / 37281 FlyBaseID:FBgn0034484 Length:511 Species:Drosophila melanogaster


Alignment Length:547 Identity:108/547 - (19%)
Similarity:184/547 - (33%) Gaps:207/547 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 RY-DDLPLEIVLKIFSYLGYSDLQAAGSTCQRWHAA----------------LDQAEFN------ 51
            || .||.||   :||:||...:...||..|::|:.|                |.:.:||      
  Fly    52 RYLPDLVLE---QIFTYLTPKERYYAGLVCRQWYRAFYLPTVWNNFLVDDRTLTKPKFNYYSGWQ 113

  Fly    52 -----QRTRVCFSKVVLSDQLSPGVDLMRCERRFQHFLFEDVTLGQVKELMRFMGRTAQSLALDN 111
                 .||:.|.|::   .:...|::.    |.:..|          ..:.:||     ::...|
  Fly   114 FCLDHMRTQFCLSRI---GRYVRGIEF----RPWHSF----------NNIFQFM-----TMLTWN 156

  Fly   112 VDLN-----DKQFYGM---LGVLPHLHSLSLKR-----CLPLFMSGSFLDSYNNSCPDLNDLASN 163
            :|..     |.||.|:   :..|.:....::.:     .:.||.:|..|                
  Fly   157 IDKGREVNPDTQFIGIGSRIRTLVYHFPCNMSQPNDPEGIKLFGTGGQL---------------- 205

  Fly   164 LAGIKELTLCENQYLTDAILMRLTSFMPSLEAINMSGCHIAFHNAIHRRFYPATSSSDHVLPS-- 226
            |..:|||.|    .|||...::|..|:  ||.                  |.|....|.|:.|  
  Fly   206 LRVLKELLL----RLTDLHTLKLVDFV--LER------------------YEANHLLDEVVCSCC 246

  Fly   227 --ESVLTFKFILTI----------LNLQRRTLRVLNFSHTLIGQALLALCDLNLQLQRLYLAGCR 279
              ..||....:.|:          ||||..|:...|....::  :|||    :.:|:.|:|.   
  Fly   247 TKMRVLNLVNVTTMHCPIMHVGLFLNLQVLTISPQNIDDDVL--SLLA----DTKLRHLHLL--- 302

  Fly   280 QLNCTTILNFLATQPQLCALDLSATMCVNDENLAALVQTNPQLE-HLKV----NGCLSITNAGAI 339
             .||.|..:          |.:||.......|:.   :|||:|. ||::    :|.:.:.....:
  Fly   303 -QNCYTPSH----------LTISACGVKAWRNVK---KTNPRLRVHLRLENLTDGEVVLQPEAPV 353

  Fly   340 H-----LAKLKCLKSLDISNCDNLTSSGIIEGIA-----SEENPVIQELNVSYLQICEECIKA-- 392
            |     ..:.:....|.:...|:..|:..:.|..     |...|....::...|.:|.:|...  
  Fly   354 HSITYCAPQTRIRAELLVRMVDHYKSTLAVYGHELLPRFSSPKPFHSRIDSLMLLMCRQCFNVDT 418

  Fly   393 --------------IASNLRCLRSLHLNHCV-----------------------NGATDEAIQSV 420
                          ||...:.|:.||:....                       |..:.||::..
  Fly   419 LIIREKVSTSTLLLIAKTAKNLQHLHVRRFAVILRCDWPRHPEWSNEFYAWLKRNSRSYEAVERE 483

  Fly   421 IGQL---RW-------LRELSLEHCSG 437
            |.|:   :|       .::|::...||
  Fly   484 ISQILGYKWRLLSDRDFKQLTVNVKSG 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 41/233 (18%)
leucine-rich repeat 270..295 CDD:275381 6/24 (25%)
leucine-rich repeat 296..319 CDD:275381 4/22 (18%)
leucine-rich repeat 322..346 CDD:275381 5/33 (15%)
leucine-rich repeat 347..399 CDD:275381 11/72 (15%)
leucine-rich repeat 400..426 CDD:275381 8/51 (16%)
leucine-rich repeat 427..535 CDD:275381 3/11 (27%)
AMN1 515..>642 CDD:187754
leucine-rich repeat 536..560 CDD:275381
leucine-rich repeat 561..586 CDD:275381
leucine-rich repeat 587..612 CDD:275381
leucine-rich repeat 613..638 CDD:275381
leucine-rich repeat 639..663 CDD:275381
F-box-like 12..>44 CDD:289689 12/31 (39%)
leucine-rich repeat 129..166 CDD:275381 5/41 (12%)
leucine-rich repeat 167..192 CDD:275381 9/24 (38%)
leucine-rich repeat 193..244 CDD:275381 14/64 (22%)
C2 <231..274 CDD:301316 11/52 (21%)
leucine-rich repeat 246..269 CDD:275381 4/22 (18%)
CG11044NP_611456.1 F-box-like 51..94 CDD:289689 15/44 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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