Protein Alignment CG8272 and Fbxl2

DIOPT Version :10

• Sequence 1: NP_001260812.1
• Gene: CG8272 / 35875
• FlyBaseID: FBgn0033337
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: XP_038938600.1
• Gene: Fbxl2 / 363156
• RGDID: 1562243
• Length: 439
• Species: Rattus norvegicus
• Alignment Length: 413
• Identity: 101/413 - (24%)
• Similarity: 171/413 - (41%)
• Gaps: 108/413 - (26%)

  Fly   299 LDLSATMCVNDENLAALVQTNPQLEHLKVNGCLSITNAGAIHLAKLKC--LKSLDISNCDNLTSS 361
            |.|...:.|.|.:|....|....:|||.:|||..||::....|::. |  ||.||:::|.::|:|
  Rat    99 LSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRF-CSKLKHLDLTSCVSVTNS 162

  Fly   362 ---GIIEGIASEENPVIQELNVSYL-QICEECIKAIASNLRCLRSLHLNHCVNGATDEAIQSVIG 422
               ||.||..:     ::.||:|:. ||.:|.|:|:....|.|::|.|..|.. ..|||::.:..
  Rat   163 SLKGISEGCRN-----LEYLNLSWCDQITKEGIEALVRGCRGLKALLLRGCTQ-LEDEALKHIQN 221

  Fly   423 QLRWLRELSLEHCSGLTDAALTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAGSLQ 487
            ....|..|:|:.||.:||..:.
  Rat   222 HCHELVSLNLQSCSRITDDGVV------------------------------------------- 243

  Fly   488 SIKISLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRGCNKISDVSL 552
                        :|.|...|.||                            |.|.||:.::|.||
  Rat   244 ------------QICRGCHRLQA----------------------------LCLSGCSNLTDASL 268

  Fly   553 -KYGLKHIELRRLMLSNCQQISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVVTSKLPRLKAL 616
             ..||....|:.|..:.|..::..|...:|.:|..:|::||.:|..|||.|:..::...|:|:||
  Rat   269 TALGLNCPRLQVLEAARCSHLTDAGFTLLARNCHDLEKMDLEECVLITDSTLIQLSIHCPKLQAL 333

  Fly   617 HISGCSQLTEHTLDAIITNCSC----LQTLSIYRCRSMYTDLE-ERLSGVKTLRNLNMDNLTSID 676
            .:|.|..:|:..: ..:::.:|    |:.|.:..| .:.||.. |.|...:.|..|.:.:...:.
  Rat   334 SLSHCELITDEGI-LHLSSSTCGHERLRVLELDNC-LLVTDASLEHLENCRGLERLELYDCQQVT 396

  Fly   677 NAEFFRLKKRLD----YXYFAAI 695
            .|...|::.:|.    :.|||.:
  Rat   397 RAGIKRMRAQLPRVKVHAYFAPV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8272	NP_001260812.1	F-box_SF	11..58	CDD:459239
		leucine-rich repeat	129..166	CDD:275381
		leucine-rich repeat	167..192	CDD:275381
		leucine-rich repeat	193..244	CDD:275381
		C2	<231..274	CDD:472691
		leucine-rich repeat	246..269	CDD:275381
		AMN1	269..440	CDD:187754	48/146 (33%)
		leucine-rich repeat	270..295	CDD:275381
		leucine-rich repeat	296..319	CDD:275381	6/19 (32%)
		leucine-rich repeat	322..346	CDD:275381	9/23 (39%)
		leucine-rich repeat	347..399	CDD:275381	19/55 (35%)
		leucine-rich repeat	400..426	CDD:275381	7/25 (28%)
		leucine-rich repeat	427..535	CDD:275381	12/107 (11%)
		AMN1	515..>642	CDD:187754	32/131 (24%)
		leucine-rich repeat	536..560	CDD:275381	9/24 (38%)
		leucine-rich repeat	561..586	CDD:275381	6/24 (25%)
		leucine-rich repeat	587..612	CDD:275381	8/24 (33%)
		leucine-rich repeat	613..638	CDD:275381	6/24 (25%)
		leucine-rich repeat	639..663	CDD:275381	7/24 (29%)
Fbxl2	XP_038938600.1	F-box_SF	<38..69	CDD:459239
		leucine-rich repeat	68..95	CDD:275381
		AMN1	<92..239	CDD:187754	48/146 (33%)
		leucine-rich repeat	96..115	CDD:275381	5/15 (33%)
		leucine-rich repeat	122..147	CDD:275381	10/25 (40%)
		leucine-rich repeat	148..173	CDD:275381	11/24 (46%)
		leucine-rich repeat	174..199	CDD:275381	8/24 (33%)
		AMN1	184..383	CDD:187754	63/284 (22%)
		leucine-rich repeat	200..225	CDD:275381	7/25 (28%)
		leucine-rich repeat	226..251	CDD:275381	9/79 (11%)
		leucine-rich repeat	252..277	CDD:275381	11/52 (21%)
		leucine-rich repeat	278..303	CDD:275381	6/24 (25%)
		leucine-rich repeat	304..329	CDD:275381	8/24 (33%)
		leucine-rich repeat	330..352	CDD:275381	6/22 (27%)
		leucine-rich repeat	359..378	CDD:275381	6/19 (32%)
		leucine-rich repeat	384..409	CDD:275381	5/24 (21%)