DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8272 and Fbxl22

DIOPT Version :9

Sequence 1:	NP_001260812.1	Gene:	CG8272 / 35875	FlyBaseID:	FBgn0033337	Length:	710	Species:	Drosophila melanogaster
Sequence 2:	NP_001102239.1	Gene:	Fbxl22 / 363083	RGDID:	1311830	Length:	236	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	46/179 - (25%)
Similarity:	85/179 - (47%)	Gaps:	24/179 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 ERDSLAGSLQSIKISLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLR 542
            ::|| ..||......||...||..:      .::|..:.:..:::|:|     :....||||::
  Rat    19 DKDS-RKSLSRTCSQLRDVFEDPTL------WSLLHFHSLTELKKDNF-----RLSPALRSLSI- 70

  Fly   543 GC---NKISDVSLKYGLKHIELRRLMLSNCQQISLLGME---AMASSCPSIEELDLSDCYNITDK 601
             |   :::...|::..||....|    |.|.|...|..:   .:.:.||::..:.||.|.::||.
  Rat    71 -CWHSSRVQVCSIEDWLKSAFQR----SICSQHENLVNDFLLQVCNRCPNLASVTLSGCGHVTDD 130

  Fly   602 TIQVVTSKLPRLKALHISGCSQLTEHTLDAIITNCSCLQTLSIYRCRSM 650
            .:..:....|||:||.:..|:::|..||.|:..:...|||..:..||::
  Rat   131 CLARLLLGCPRLRALRLENCARVTNRTLAAVAAHGRALQTFHVDFCRNV 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8272	NP_001260812.1	AMN1	269..440	CDD:187754
		leucine-rich repeat	270..295	CDD:275381
		leucine-rich repeat	296..319	CDD:275381
		leucine-rich repeat	322..346	CDD:275381
		leucine-rich repeat	347..399	CDD:275381
		leucine-rich repeat	400..426	CDD:275381
		leucine-rich repeat	427..535	CDD:275381	11/56 (20%)
		AMN1	515..>642	CDD:187754	34/132 (26%)
		leucine-rich repeat	536..560	CDD:275381	8/26 (31%)
		leucine-rich repeat	561..586	CDD:275381	6/27 (22%)
		leucine-rich repeat	587..612	CDD:275381	5/24 (21%)
		leucine-rich repeat	613..638	CDD:275381	8/24 (33%)
		leucine-rich repeat	639..663	CDD:275381	5/12 (42%)
		F-box-like	12..>44	CDD:289689
		leucine-rich repeat	129..166	CDD:275381
		leucine-rich repeat	167..192	CDD:275381
		leucine-rich repeat	193..244	CDD:275381
		C2	<231..274	CDD:301316
		leucine-rich repeat	246..269	CDD:275381
Fbxl22	NP_001102239.1	F-box-like	3..43	CDD:403981	8/30 (27%)
		AMN1	44..>191	CDD:187754	38/147 (26%)
		leucine-rich repeat	116..141	CDD:275381	5/24 (21%)
		leucine-rich repeat	142..167	CDD:275381	8/24 (33%)
		leucine-rich repeat	168..193	CDD:275381	5/12 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830