DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8272 and fbxl14a

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_958890.1 Gene:fbxl14a / 333988 ZFINID:ZDB-GENE-030131-5920 Length:411 Species:Danio rerio


Alignment Length:540 Identity:120/540 - (22%)
Similarity:193/540 - (35%) Gaps:217/540 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 GVLPHLHSLSLKRCLP-LFMSGSFLDSYNNSCPDLNDLASNLAGIKELTLCENQYLTDAILMRLT 187
            ||...||   |:|..| ||             |.|     ...|||::.:..        |.|..
Zfish    47 GVEAKLH---LRRANPSLF-------------PSL-----QTRGIKKVQILS--------LRRSL 82

  Fly   188 SF----MPSLEAINMSGCHIAFHNAIHRRFYPATSSSDHVLPSESVLTFKFILTILNLQRRTLRV 248
            |:    ||::|::|:|||:....|.:...|.       ..:||                   ||:
Zfish    83 SYVIQGMPNIESLNLSGCYNLTDNGLGHAFV-------QDIPS-------------------LRI 121

  Fly   249 LNFSHTLIGQALLALCDLNLQLQRLYLAGCRQLNCTTILNFLATQPQLCALDLSATMCVNDENLA 313
            ||                        |:.|:|                          :.|.:|.
Zfish   122 LN------------------------LSLCKQ--------------------------ITDSSLG 136

  Fly   314 ALVQTNPQLEHLKVNGCLSITNAGAIHLA-KLKCLKSLDISNCDNLTSSGI--IEGI---ASEEN 372
            .:.|....||.|.:.||.:|||.|.:.:| .|..||||::.:|.:::..||  :.|:   |:|..
Zfish   137 RIAQYLKNLELLDLGGCSNITNTGLLLIAWGLHNLKSLNLRSCRHVSDVGIGHLAGMTRSAAEGC 201

  Fly   373 PVIQELNVSYLQICEECIKAIASNLRCLRSLHLNHCVNGATDEAIQSVIGQLRWLRELSLEHCSG 437
            ..::.|.   ||.|::           |..|.|.|...|            |..|:.|:|..|.|
Zfish   202 LTLEHLT---LQDCQK-----------LTDLSLKHISKG------------LNKLKVLNLSFCGG 240

  Fly   438 LTDAALTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAGSLQSIKISLRSKAEDEIV 502
            ::||.:  |::|.                                                    
Zfish   241 ISDAGM--IHLSH---------------------------------------------------- 251

  Fly   503 RDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRG-----CNKISDVSLKY---GLKHI 559
                    |...:.:||...|:.....|..| .:.:|.|.|     |:|:.|.||.|   ||  .
Zfish   252 --------MTQLWTLNLRSCDNISDTGIMHL-SMGALRLYGLDVSFCDKVGDQSLAYIAQGL--Y 305

  Fly   560 ELRRLMLSNCQQISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVVTSKLPRLKALHISGCSQL 624
            :|:.|.|.:| .||..|:..|......::.|::..|..||||.::::...|.:|..:.:.||:::
Zfish   306 QLKSLSLCSC-HISDDGINRMVRQMHELKTLNIGQCVRITDKGLELIADHLTQLTGIDLYGCTKI 369

  Fly   625 TEHTLDAIITNCSCLQTLSI 644
            |:..|:. ||...||:.|::
Zfish   370 TKRGLER-ITQLPCLKVLNL 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 42/176 (24%)
leucine-rich repeat 270..295 CDD:275381 3/24 (13%)
leucine-rich repeat 296..319 CDD:275381 3/22 (14%)
leucine-rich repeat 322..346 CDD:275381 11/24 (46%)
leucine-rich repeat 347..399 CDD:275381 14/56 (25%)
leucine-rich repeat 400..426 CDD:275381 6/25 (24%)
leucine-rich repeat 427..535 CDD:275381 15/107 (14%)
AMN1 515..>642 CDD:187754 40/134 (30%)
leucine-rich repeat 536..560 CDD:275381 11/31 (35%)
leucine-rich repeat 561..586 CDD:275381 8/24 (33%)
leucine-rich repeat 587..612 CDD:275381 7/24 (29%)
leucine-rich repeat 613..638 CDD:275381 7/24 (29%)
leucine-rich repeat 639..663 CDD:275381 2/6 (33%)
F-box-like 12..>44 CDD:289689
leucine-rich repeat 129..166 CDD:275381 9/37 (24%)
leucine-rich repeat 167..192 CDD:275381 6/28 (21%)
leucine-rich repeat 193..244 CDD:275381 9/50 (18%)
C2 <231..274 CDD:301316 4/42 (10%)
leucine-rich repeat 246..269 CDD:275381 4/22 (18%)
fbxl14aNP_958890.1 F-box-like 5..46 CDD:289689
AMN1 90..243 CDD:187754 56/254 (22%)
leucine-rich repeat 92..118 CDD:275381 7/32 (22%)
leucine-rich repeat 119..144 CDD:275381 10/74 (14%)
leucine-rich repeat 145..170 CDD:275381 11/24 (46%)
leucine-rich repeat 171..203 CDD:275381 10/31 (32%)
leucine-rich repeat 204..229 CDD:275381 10/50 (20%)
AMN1 230..397 CDD:187754 51/226 (23%)
leucine-rich repeat 230..254 CDD:275381 10/85 (12%)
leucine-rich repeat 255..280 CDD:275381 5/25 (20%)
leucine-rich repeat 281..304 CDD:275381 8/22 (36%)
leucine-rich repeat 307..331 CDD:275381 8/24 (33%)
leucine-rich repeat 332..357 CDD:275381 7/24 (29%)
leucine-rich repeat 358..377 CDD:275381 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR13318
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.910

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