DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8272 and CG15056

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_573291.1 Gene:CG15056 / 32824 FlyBaseID:FBgn0030918 Length:399 Species:Drosophila melanogaster


Alignment Length:328 Identity:75/328 - (22%)
Similarity:109/328 - (33%) Gaps:113/328 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 FQHFLFEDVTLGQVKELMRFMGRTAQSLALDNVDLND-KQFYGMLGVLPHLHSLSLKRCLPLFMS 143
            |.|  |||..     .||.........:||:...|.. |.|........:|..:||:||      
  Fly    90 FSH--FEDFI-----RLMSIRLTKVNEIALEGFQLTQYKWFNAPETSFSNLTYVSLRRC------ 141

  Fly   144 GSFLDSYNNSCPDLNDLASNLAGIKELTLCE------NQYLTDAILMRLTSFMPSLEAINMSGC- 201
                        .|||  .||.|.:.||..|      |..||.:.||.|.:   ||.::.::|| 
  Fly   142 ------------QLND--ENLVGWEFLTHLETLDLRYNDRLTGSCLMSLPT---SLLSLYITGCR 189

  Fly   202 -----HIAFHNAI---------------HRRFYPATSSSDHVLPSESVLTFKFILTILNLQRRTL 246
                 .:.|.|.|               |...|     .|.||....::..:..:..||.....|
  Fly   190 NLCPNQLIFLNRIPRLRELRASDLMPGGHWHIY-----RDLVLACPLLVMVEISICSLNRDEYRL 249

  Fly   247 RVLNFSHTLIGQA--------------LLALCDLNLQLQRLY---------------LAGCRQLN 282
            ..|.:..:|:.:|              |::|.|:......::               ::..|||.
  Fly   250 GELRYLQSLVIKAHSTDTIRCKVSDWMLISLLDVPFLRNLMFSDAPSGFVSANALSIISRFRQLR 314

  Fly   283 CTTI---------------LNFLATQPQLCALDLSATMCVNDENLAALVQTNPQLEHLKVNGCLS 332
            ...:               |.||.|      ||||.:..:.:|.:..||...|.|..|.|.||..
  Fly   315 VLKMPNQPYRPNDLLRLRNLTFLET------LDLSNSPYITNEVVIELVIGIPNLSVLIVQGCPL 373

  Fly   333 ITN 335
            :||
  Fly   374 LTN 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 22/97 (23%)
leucine-rich repeat 270..295 CDD:275381 7/54 (13%)
leucine-rich repeat 296..319 CDD:275381 7/22 (32%)
leucine-rich repeat 322..346 CDD:275381 7/14 (50%)
leucine-rich repeat 347..399 CDD:275381
leucine-rich repeat 400..426 CDD:275381
leucine-rich repeat 427..535 CDD:275381
AMN1 515..>642 CDD:187754
leucine-rich repeat 536..560 CDD:275381
leucine-rich repeat 561..586 CDD:275381
leucine-rich repeat 587..612 CDD:275381
leucine-rich repeat 613..638 CDD:275381
leucine-rich repeat 639..663 CDD:275381
F-box-like 12..>44 CDD:289689
leucine-rich repeat 129..166 CDD:275381 10/36 (28%)
leucine-rich repeat 167..192 CDD:275381 9/30 (30%)
leucine-rich repeat 193..244 CDD:275381 13/71 (18%)
C2 <231..274 CDD:301316 9/56 (16%)
leucine-rich repeat 246..269 CDD:275381 7/36 (19%)
CG15056NP_573291.1 leucine-rich repeat 133..156 CDD:275381 12/42 (29%)
leucine-rich repeat 157..179 CDD:275381 7/24 (29%)
leucine-rich repeat 180..204 CDD:275381 6/23 (26%)
leucine-rich repeat 205..231 CDD:275381 5/30 (17%)
leucine-rich repeat 232..285 CDD:275381 9/52 (17%)
leucine-rich repeat 286..326 CDD:275381 3/39 (8%)
AMN1 306..>376 CDD:187754 20/75 (27%)
leucine-rich repeat 337..362 CDD:275381 9/30 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457976
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.830

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