Protein Alignment CG8272 and fbxl14b

DIOPT Version :9

• Sequence 1: NP_001260812.1
• Gene: CG8272 / 35875
• FlyBaseID: FBgn0033337
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001015043.1
• Gene: fbxl14b / 324835
• ZFINID: ZDB-GENE-030131-3556
• Length: 400
• Species: Danio rerio
• Alignment Length: 637
• Identity: 130/637 - (20%)
• Similarity: 205/637 - (32%)
• Gaps: 268/637 - (42%)

  Fly    17 EIVLKIFSYLGYSDLQAAGSTCQRWHAALDQAEFNQRTRVCFSKVVLSDQLSPGVDLMRCERRFQ 81
            ||:..|||||...|.......|..|..|            .:.|.|..     ||:.....||..
Zfish    11 EILAMIFSYLDVRDKGRVAQVCTAWRDA------------SYHKSVWR-----GVEAKLHLRRAN 58

  Fly    82 HFLFEDVTLGQVKELMRFMGRTAQSLALDNVDLNDKQFYGMLGVLPHLHSLSLKRCLPLFMSGSF 146
            ..||..:   |.:.:.|                              :..|||:|.|...:.|
Zfish    59 PSLFPSL---QARGIRR------------------------------VQILSLRRSLSYVIQG-- 88

  Fly   147 LDSYNNSCPDLNDLASNLAGIKELTLCENQYLTDAILMRLTSFMPSLEAINMSGCHIAFHNAIHR 211
                                                       ||::|::|:|||:....|.:..
Zfish    89 -------------------------------------------MPNIESLNLSGCYNLTDNGLGH 110

  Fly   212 RFYPATSSSDHVLPSESVLTFKFILTILNLQRRTLRVLNFSHTLIGQALLALCDLNLQLQRLYLA 276
            .|.       ..:||                   |||||                        |:
Zfish   111 AFV-------QEIPS-------------------LRVLN------------------------LS 125

  Fly   277 GCRQLNCTTILNFLATQPQLCALDLSATMCVNDENLAALVQTNPQLEHLKVNGCLSITNAGAIHL 341
            .|:|                          :.|.:|..:.|....||.|::.||.:|||.|.:.:
Zfish   126 LCKQ--------------------------ITDSSLGRIAQYLKNLEVLELGGCSNITNTGLLLI 164

  Fly   342 A-KLKCLKSLDISNCDNLTSSGIIEGIASEENPVIQELNVSYLQICEECIKAIASNLRCLRSLHL 405
            | .|..||||::.:|.:::..||........:.....|::.||.: ::|.|        |..|.|
Zfish   165 AWGLHRLKSLNLRSCRHVSDVGIGHLAGMTRSAAEGCLSLEYLTL-QDCQK--------LTDLSL 220

  Fly   406 NHCVNGATDEAIQSVIGQLRWLRELSLEHCSGLTDAALTGINISKLEMSRKQSGSQVSSMDNFYP 470
            .|...|.|.            |:.|:|..|.|::||.:  |::|.
Zfish   221 KHISKGLTK------------LKVLNLSFCGGISDAGM--IHLSH-------------------- 251

  Fly   471 PYSNTLAERDSLAGSLQSIKISLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRG 535
                                                    |.:.:.:||...|:.....|..| .
Zfish   252 ----------------------------------------MTSLWSLNLRSCDNISDTGIMHL-A 275

  Fly   536 LRSLNLRG-----CNKISDVSLKY---GLKHIELRRLMLSNCQQISLLGMEAMASSCPSIEELDL 592
            :.:|.|.|     |:||.|.||.|   ||  .:|:.|.|.:| .||..|:..|......:..|::
Zfish   276 MGTLRLSGLDVSFCDKIGDQSLAYIAQGL--YQLKSLSLCSC-HISDDGINRMVRQMHELRTLNI 337

  Fly   593 SDCYNITDKTIQVVTSKLPRLKALHISGCSQLTEHTLDAIITNCSCLQTLSI 644
            ..|..||||.::::...|.:|..:.:.||:::|:..|:. ||...||:.|::
Zfish   338 GQCVRITDKGLELIADHLTQLTGIDLYGCTKITKRGLER-ITQLPCLKVLNL 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8272	NP_001260812.1	AMN1	269..440	CDD:187754	40/171 (23%)
		leucine-rich repeat	270..295	CDD:275381	3/24 (13%)
		leucine-rich repeat	296..319	CDD:275381	3/22 (14%)
		leucine-rich repeat	322..346	CDD:275381	11/24 (46%)
		leucine-rich repeat	347..399	CDD:275381	12/51 (24%)
		leucine-rich repeat	400..426	CDD:275381	6/25 (24%)
		leucine-rich repeat	427..535	CDD:275381	15/107 (14%)
		AMN1	515..>642	CDD:187754	41/134 (31%)
		leucine-rich repeat	536..560	CDD:275381	12/31 (39%)
		leucine-rich repeat	561..586	CDD:275381	8/24 (33%)
		leucine-rich repeat	587..612	CDD:275381	7/24 (29%)
		leucine-rich repeat	613..638	CDD:275381	7/24 (29%)
		leucine-rich repeat	639..663	CDD:275381	2/6 (33%)
		F-box-like	12..>44	CDD:289689	10/26 (38%)
		leucine-rich repeat	129..166	CDD:275381	6/36 (17%)
		leucine-rich repeat	167..192	CDD:275381	1/24 (4%)
		leucine-rich repeat	193..244	CDD:275381	9/50 (18%)
		C2	<231..274	CDD:301316	5/42 (12%)
		leucine-rich repeat	246..269	CDD:275381	5/22 (23%)
fbxl14b	NP_001015043.1	F-box-like	5..46	CDD:403981	13/46 (28%)
		AMN1	90..296	CDD:187754	72/365 (20%)
		leucine-rich repeat	92..118	CDD:275381	7/32 (22%)
		leucine-rich repeat	119..144	CDD:275381	11/74 (15%)
		leucine-rich repeat	145..170	CDD:275381	11/24 (46%)
		leucine-rich repeat	171..203	CDD:275381	7/31 (23%)
		leucine-rich repeat	204..229	CDD:275381	9/33 (27%)
		AMN1	230..388	CDD:187754	52/224 (23%)
		leucine-rich repeat	230..254	CDD:275381	10/85 (12%)
		leucine-rich repeat	255..280	CDD:275381	5/25 (20%)
		leucine-rich repeat	281..304	CDD:275381	9/22 (41%)
		leucine-rich repeat	307..331	CDD:275381	8/24 (33%)
		leucine-rich repeat	332..357	CDD:275381	7/24 (29%)
		leucine-rich repeat	358..382	CDD:275381	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13318
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910