DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8272 and Fbxl17

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:XP_038939705.1 Gene:Fbxl17 / 316663 RGDID:1309773 Length:739 Species:Rattus norvegicus


Alignment Length:357 Identity:83/357 - (23%)
Similarity:143/357 - (40%) Gaps:104/357 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   131 SLSL-KRCLPLFMSGSFLDSYNNSCPDLNDLASNLAGIKELTLCENQYLTDAILMRLTSFMPSLE 194
            :||| :|||    |.|.:      |....||..:....|:|.|...|.:||.:|.::.|...::.
  Rat   330 NLSLDERCL----SASLV------CKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQN
IV 384

  Fly   195 AINMSGCH---------IAFH--NAIHRRFYPATSSSD----------------HVLPSESVLTF 232
            .||:|.|.         :||.  ..:....|.....||                || .::..||.
  Rat   385 EINISDCRSMSDSGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHV-GNQDKLTD 448

  Fly   233 KFILTILNLQRRTLRVLNFS--HTLIGQALLALCDLNLQLQRLYLAGCRQLNCTTILNFLATQPQ 295
            :. |..|..:.|.|:.::|.  :.:..:.::.:....|:|||:|                     
  Rat   449 EG-LKQLGSKCRELKDIHFGQCYKISDEGMVVIAKSCLKLQRIY--------------------- 491

  Fly   296 LCALDLSATMCVNDENLAALVQTNPQLEHLKVNGCLSITNAGAIHLAKLKCLKSLDISNCDNLTS 360
                 :.....|.|:::.|..:..|.|:.:...|| |:|:.|.|||.||:.|.|||:.:...|.:
  Rat   492 -----MQENKLVTDQSVKAFAEHCPDLQCVGFMGC-SVTSKGVIHLTKLRNLSSLDLRHITELDN 550

  Fly   361 SGIIEGIASEENPVIQEL-NVSYLQIC------EECIKAIASNLRCLRSLHLNHCV--------- 409
            ..::|        :::.. |:|.|.:|      :.|::.||...:.|:.|:|..|.         
  Rat   551 ETVME--------IVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQSLKELYLVSCKITDYGQRGN 607

  Fly   410 NGATDEAIQSVIGQLRWLRELSLEHC-SGLTD 440
            :||...|:.|          ..|:|| :||.:
  Rat   608 SGAAGTAVPS----------HHLQHCPAGLQE 629

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 45/187 (24%)
leucine-rich repeat 270..295 CDD:275381 4/24 (17%)
leucine-rich repeat 296..319 CDD:275381 3/22 (14%)
leucine-rich repeat 322..346 CDD:275381 11/23 (48%)
leucine-rich repeat 347..399 CDD:275381 13/58 (22%)
leucine-rich repeat 400..426 CDD:275381 8/34 (24%)
leucine-rich repeat 427..535 CDD:275381 5/15 (33%)
AMN1 515..>642 CDD:187754
leucine-rich repeat 536..560 CDD:275381
leucine-rich repeat 561..586 CDD:275381
leucine-rich repeat 587..612 CDD:275381
leucine-rich repeat 613..638 CDD:275381
leucine-rich repeat 639..663 CDD:275381
F-box-like 12..>44 CDD:289689
leucine-rich repeat 129..166 CDD:275381 11/35 (31%)
leucine-rich repeat 167..192 CDD:275381 8/24 (33%)
leucine-rich repeat 193..244 CDD:275381 15/77 (19%)
C2 <231..274 CDD:301316 10/44 (23%)
leucine-rich repeat 246..269 CDD:275381 2/24 (8%)
Fbxl17XP_038939705.1 F-box-like 316..361 CDD:403981 12/40 (30%)
leucine-rich repeat 357..382 CDD:275381 8/24 (33%)
leucine-rich repeat 383..408 CDD:275381 6/24 (25%)
AMN1 406..568 CDD:187754 41/198 (21%)
leucine-rich repeat 409..434 CDD:275381 3/24 (13%)
leucine-rich repeat 435..460 CDD:275381 6/26 (23%)
leucine-rich repeat 461..486 CDD:275381 2/24 (8%)
leucine-rich repeat 487..512 CDD:275381 7/50 (14%)
leucine-rich repeat 513..536 CDD:275381 11/23 (48%)
leucine-rich repeat 537..562 CDD:275381 6/32 (19%)
leucine-rich repeat 563..588 CDD:275381 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166346615
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.830

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