DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8272 and Amn1

DIOPT Version :9

Sequence 1:NP_001260812.1 Gene:CG8272 / 35875 FlyBaseID:FBgn0033337 Length:710 Species:Drosophila melanogaster
Sequence 2:NP_001106895.1 Gene:Amn1 / 232566 MGIID:2442933 Length:258 Species:Mus musculus


Alignment Length:297 Identity:71/297 - (23%)
Similarity:123/297 - (41%) Gaps:81/297 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   417 IQSVIGQLRWLRELSLEHCSGLTDAALTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDS 481
            :..|:.|   |.||.|::..         ||||:.....|...|.:                :|.
Mouse     3 LSGVVSQ---LLELCLQYLV---------INISRYISDIKYLPSNI----------------KDR 39

  Fly   482 LAGSLQSIKI-SLRSKAEDEIVRDARRKQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRGCN 545
            |      ||| |:|.:..|..:.:....:                          ::.|:||.|:
Mouse    40 L------IKIMSIRGRITDSNISEVLHPE--------------------------VQRLDLRSCD 72

  Fly   546 KISDVSLKYGLKHIELRRLMLSNCQQ----ISLLGMEAMASSCPSIEELDLSDCYNITDKTIQVV 606
             ||||:|::..|..:|:.|.|.:|::    |:..|::|:||||..:.|:.|..|.::||:.:..:
Mouse    73 -ISDVALQHLCKCRKLKALNLKSCREHRNSITSEGIKAVASSCSDLHEIYLKGCCSVTDEGVLAL 136

  Fly   607 TSKLPRLKALHISGCSQLTEHTLDAIITNCSCLQTLSIYRCRSMYTDLEERLSG--VKTLRNLNM 669
            ......||.:.:.||..:|:.:|.|:..||..||.:.|...:.....:...:||  .|.|..:||
Mouse   137 ALNCHLLKIIDLGGCLGITDVSLHALGKNCPFLQCVDISTTQVSDNGVVALVSGPCAKQLEEINM 201

  Fly   670 D---NLTSIDNAEFFRLKKRLDYXYFAAIFIVLMLYY 703
            .   |||.          |.::....|...|.::|::
Mouse   202 RYCINLTD----------KAVEAALTACPRICILLFH 228

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8272NP_001260812.1 AMN1 269..440 CDD:187754 6/22 (27%)
leucine-rich repeat 270..295 CDD:275381
leucine-rich repeat 296..319 CDD:275381
leucine-rich repeat 322..346 CDD:275381
leucine-rich repeat 347..399 CDD:275381
leucine-rich repeat 400..426 CDD:275381 2/8 (25%)
leucine-rich repeat 427..535 CDD:275381 18/108 (17%)
AMN1 515..>642 CDD:187754 37/130 (28%)
leucine-rich repeat 536..560 CDD:275381 10/23 (43%)
leucine-rich repeat 561..586 CDD:275381 11/28 (39%)
leucine-rich repeat 587..612 CDD:275381 5/24 (21%)
leucine-rich repeat 613..638 CDD:275381 9/24 (38%)
leucine-rich repeat 639..663 CDD:275381 5/25 (20%)
F-box-like 12..>44 CDD:289689
leucine-rich repeat 129..166 CDD:275381
leucine-rich repeat 167..192 CDD:275381
leucine-rich repeat 193..244 CDD:275381
C2 <231..274 CDD:301316
leucine-rich repeat 246..269 CDD:275381
Amn1NP_001106895.1 leucine-rich repeat 15..38 CDD:275381 7/47 (15%)
AMN1 37..257 CDD:187754 59/235 (25%)
leucine-rich repeat 63..86 CDD:275381 10/23 (43%)
leucine-rich repeat 87..116 CDD:275381 11/28 (39%)
leucine-rich repeat 117..142 CDD:275381 5/24 (21%)
leucine-rich repeat 143..168 CDD:275381 9/24 (38%)
leucine-rich repeat 169..195 CDD:275381 5/25 (20%)
leucine-rich repeat 196..221 CDD:275381 8/34 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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