Protein Alignment stmA and EFR3B

DIOPT Version :9

• Sequence 1: NP_001014513.1
• Gene: stmA / 35865
• FlyBaseID: FBgn0086784
• Length: 834
• Species: Drosophila melanogaster
• Sequence 2: NP_055786.1
• Gene: EFR3B / 22979
• HGNCID: 29155
• Length: 817
• Species: Homo sapiens
• Alignment Length: 857
• Identity: 333/857 - (38%)
• Similarity: 501/857 - (58%)
• Gaps: 97/857 - (11%)

  Fly    31 CGCCSALRPRYKRLVDNIFPVNPEDGLVKSNMEKLTFYSLSSPDKLDRIGEYLYQKATKDINRKR 95
            ||||.|||||||||||||||.:|||||||:||||||||:||:|:||||||.||.::..:|:.|.|
Human     5 CGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHR 69

  Fly    96 YKLAEIAMEAMDLLLQACHAQTTLNLFVESFLRMVQKLLEDSNPNLKIMATNSFVKFANINEDTP 160
            |....|||||:|.||.|||.| ::||||||||:||.||||...|||:|:.||||||||||.||||
Human    70 YGYVCIAMEALDQLLMACHCQ-SINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTP 133

  Fly   161 SYHRRYDFFISKFSSMCHS--DAASMRDSLRLAGIKGLQGVIRKTVSDDLVENIWEAEHMEKIVP 223
            ||||.||||:|:||.||||  |...::..:|::||||||||:||||:|:|..|||:.:||:||||
Human   134 SYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVP 198

  Fly   224 SLLFNMQFCVNVMFVKKNLLASGDLTPVEDATNVTP------------PA-LAEEVLRELVGRAS 275
            |||||:|.                   ||:|.:.:|            || |||..||||:|||:
Human   199 SLLFNLQH-------------------VEEAESRSPSPLQAPEKEKESPAELAERCLRELLGRAA 244

  Fly   276 FGHIRSVLKPLLTHLDRHELWVPNTFAIHTFRIVMISIQPQYSYTVVETLMQHLDNNFKSSPKTR 340
            ||:|::.:||:|.|||.|.||.|..|||..|:|:|.|||||:|:.|::.|:.|||.|.:|:...|
Human   245 FGNIKNAIKPVLIHLDNHSLWEPKVFAIRCFKIIMYSIQPQHSHLVIQQLLGHLDANSRSAATVR 309

  Fly   341 TSLAVVLSKIIAIAAGESVGPSALDIINNLLTHLRTS------------VSTTSEITP--EESQY 391
            ..:..|||:...|||..||||:.|::.|.||..||.|            ||..::|..  ||..:
Human   310 AGIVEVLSEAAVIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGTKIIKEHEERMF 374

  Fly   392 QEALINALGEFANHHPDYQKIEIMLFIMNTVP--------DLSKKSKG-DQMLQNILLKSLLKVG 447
            |||:|..:|.||:..|.||:.|::||||:.||        |..:..:. :::.|.:||||||:|.
Human   375 QEAVIKTVGSFASTLPTYQRSEVILFIMSKVPRPSLHQAVDTGRTGENRNRLTQIMLLKSLLQVS 439

  Fly   448 TQYSTVSFEKAFPASFLQPLLKMARAPHNPTRMVVMQILQALLDRHQNE------QVLSSVSVKP 506
            |.:...:...|.|::||..||..|.......|:.|::||.:.:|||.|.      ..||.:||.
Human   440 TGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLSDISVL- 503

  Fly   507 YPALSQEPPSRSDIIFTHKYGANIMQALI----DSMALSDRVDALTSSFNTAALLIVEMSCNETV 567
              .|..:..||.|.:|..|:...:.:.:.    :...:....:||   :...||:.:|::..|.|
Human   504 --KLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNVQKHYEAL---YGLLALISIELANEEVV 563

  Fly   568 QEFLLFILGIQQVA-CTVDTLGNVHKCSLHAISIGLLVLISRVSGINNLLEYAQKIVDARREEAS 631
            .:.:..:|.:|.|| ...:.|...::|:|:|:....|.|||:::.:....::..::::.|::||.
Human   564 VDLIRLVLAVQDVAQVNEENLPVYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAP 628

  Fly   632 HFLPP--LLEPKKLAGKTFNLQLPHLAIDKLALGECLQNAGMDAQRLNTGAPYSLNQTDHPGHRH 694
            :.||.  .:|..:|:.....:.: .|...:..:.|.|..:|.::.||  ..||....||
Human   629 YMLPEDVFVERPRLSQNLDGVVI-ELLFRQSKISEVLGGSGYNSDRL--CLPYIPQLTD------ 684

  Fly   695 SWVESVSNQLTQRNSSADLTVYNGDVDSVSSSPGVCKKLLAPEFNFDAMKRALAEPTEAAKREQR 759
                  .::|::|.|..:......:|:| .:||...:::.|.|..::.:|:|:.: :.|.:.::|
Human   685 ------EDRLSKRRSIGETISLQVEVES-RNSPEKEERVPAEEITYETLKKAIVD-SVAVEEQER 741

  Fly   760 ERQMQIVRTFREGEFDDLMRRTEPKHDLIQNRLNELFNSLAVERQITQSDTKSSQL-QASNEK-P 822
            ||:.|:|..|::..|:::......:..|:|::||::| .:.:....:.|.|.::.. |..|.. |
Human   742 ERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIF-EITIRPPPSPSGTITAAYGQPQNHSIP 805

  Fly   823 IYETNFPELFYY 834
            :||..||:|..|
Human   806 VYEMKFPDLCVY 817

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	548	1.000	Domainoid score	I255
eggNOG	1	0.900	-	-		E1_KOG1877
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H66195
Inparanoid	1	1.050	549	1.000	Inparanoid score	I1148
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56105
OrthoDB	1	1.010	-	-		D173880at2759
OrthoFinder	1	1.000	-	-		FOG0002866
OrthoInspector	1	1.000	-	-		otm40439
orthoMCL	1	0.900	-	-		OOG6_104012
Panther	1	1.100	-	-	O	PTHR12444
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2505
SonicParanoid	1	1.000	-	-		X1122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870