DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gcl and Btbd16

DIOPT Version :9

Sequence 1:	NP_724708.1	Gene:	gcl / 35864	FlyBaseID:	FBgn0005695	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_017444909.1	Gene:	Btbd16 / 361658	RGDID:	1311454	Length:	511	Species:	Rattus norvegicus

Alignment Length:	453	Identity:	98/453 - (21%)
Similarity:	174/453 - (38%)	Gaps:	130/453 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 YKALFKE--------EKNSDVAVMALDKVWHLHKVYLSQSP-----YFYTMFNGTWREAQQN--- 104
            ::.||.|        ...:||.:..|...|.||...:.||.     |...:...| :.:|::
  Rat    63 FQKLFTESIMDSGTQSGEADVILDCLGFKWELHHPQIFQSETLAKLYLTALIQNT-KSSQRDLEK 126

  Fly   105 -------------------FIQITILDDRITVASLDAVFGSMYSDEIEIESADVISVLATATLFH 150
                               .|.:.|.|..:|..:......::|.:|:|:...:|:.|||:|.:..
  Rat   127 ILKVHSTERMKKRSPVKKIIISLRINDPAVTRVAFALALKNLYMNEVEMTVDNVLGVLASAHILQ 191

  Fly   151 LDGII----DKCAEVMVDNISPETAIQYYEAACQYGVVGVKKSTFQWFQINLLSIYSKQPNLLRH 211
            .:.:.    .:|...|::.::|.|...:|.|.|:|....:..:..:|..:||:.:...|.: |||
  Rat   192 FNRLFRNSPHRCVSTMLNRLTPCTIKNFYLAGCKYKEEQLTNACEKWLAMNLVPLVGTQIH-LRH 255

  Fly   212 ISIELMSALTASPDLYVMQTEFSLYTLLRTWMFLRLHPDYDPEDPVQRAEALKTQELLVNAGVET 276
            |...|:..:..||.|:.. :||.|...|..|::|:::         .:.:.|...|.::
  Rat   256 IPEPLLYKVLKSPRLFTF-SEFHLLKTLLMWVYLQMN---------GKVQTLPIHETML------ 304

  Fly   277 HAPSGDVVQWTYFTSRSEERSFLATPEGQPYVKVFQKLRTQYLTNHYMDLKIIYNDNIIPKEWLY 341
                      .:|:|..::..||....|..::.:|..||...:|:. .||:.|.:.|..|:.||.
  Rat   305 ----------AFFSSFPKKSCFLEQDPGHSWMPLFLCLRLHGITSG-KDLEEIKHINFFPESWLV 358

  Fly   342 RHIHNHWDALLRIDHG-----QEDCSPQQLDDEQFFENCMRCGRMLLEP-----------GY--- 387
            |...||:.||   :.|     .:|.|.|          .||.|.:..:.           ||
  Rat   359 RVTANHYHAL---ESGGNMVHLKDLSTQ----------AMRFGLLFRQEYTTYSETISIYGYFFE 410

  Fly   388 ---QKWRWTGFNFGMDLILIMDSRRLNIRRHHRH----------EHERVLSLQTKR--KFMVR 435
               .|...|.::|.|..|              ||          ||. .:||:::|  |:.:|
  Rat   411 IKGIKHDTTSYSFSMQRI--------------RHTDLECPSSVCEHS-TISLRSERLVKYEIR 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gcl	NP_724708.1	BTB	56..163	CDD:279045	27/145 (19%)
gcl	NP_724708.1	BTB	67..166	CDD:197585	25/129 (19%)
Btbd16	XP_017444909.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4682
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740