Protein Alignment gcl and Btbd35f21

DIOPT Version :10

• Sequence 1: NP_724708.1
• Gene: gcl / 35864
• FlyBaseID: FBgn0005695
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001257598.1
• Gene: Btbd35f21 / 100862329
• MGIID: 5439402
• Length: 498
• Species: Mus musculus
• Alignment Length: 500
• Identity: 149/500 - (29%)
• Similarity: 233/500 - (46%)
• Gaps: 60/500 - (12%)

  Fly    13 AEVFSNRRKRKRSTDSSLGKDDPAQLDTTQ---PKK-------KKLLTTTQYIYKALFKEEKNSD 67
            |......|||||::...|...........|   |.:       |::..::...|:.||.:..:||
Mouse    27 ASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSD 91

  Fly    68 VAVMALDKVWHLHKVYLSQSPYFYTMFNGTWREAQQNFIQITILDDRITVASLDAVFGSMYSD-E 131
            :.:.||.:.|.||||:|.||.||..:..|||||:....|.:.|.::.|...||..|||::|:| :
Mouse    92 IKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDAD 156

  Fly   132 IEIESADVISVLATATLFHLDGIIDKCAEVMVDNISPETAIQYYEAACQYGVVGVKKSTFQWFQI 196
            :.|...:|..|||.|.|..:|.:|.:|..:|.:.|:..|...||.||..|.:..||...|:|...
Mouse   157 LSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLC 221

  Fly   197 NLLSIYSKQPN--LLRHISIELMSALTASPDLYVMQTEFSLYTLLRTWMFLRLHPDYDPEDPVQR 259
            ||:    ..|:  |.:.:.::||..|..|.||.|||.|..:||.|:.||.|.|:|.::.
Mouse   222 NLM----VHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNG------ 276

  Fly   260 AEALKTQELLVNAG--VETHAPSGDVVQWTYFTSRSEERSFLATPEGQPYVKVFQKLRTQYLTNH 322
                ..::||.:|.  :.||....|.:            |||.:.||..:..||:|||.|::...
Mouse   277 ----TMKQLLQHANNWLSTHMAYIDNI------------SFLESEEGLIFQPVFKKLRFQHIICD 325

  Fly   323 YMDLKIIYNDNIIPKEWLYRHIHNHWDALLRI-DHGQEDCSPQQLDDEQFFENCMRCGRMLLEPG 386
            .....|:..|.:||..||.......|..|||. ::|.  ..||.:::::..|..||||.|:.:.|
Mouse   326 LTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGV--IGPQVINEQELEECTMRCGTMIPKDG 388

  Fly   387 YQKWRWTGFNFGMDLILIMDSRRLNIRRHHR-------HEHERVLSLQTKRKFMVRTTVTSINAQ 444
            ...|:|:....|..|.:....:.:.:|:..:       |.|        .|..:.|.|:...::.
Mouse   389 RYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNH--------IRNVIFRITLVCFDSN 445

  Fly   445 RQAVFTQTSEICSLSLEKNEEVPLMVLDPK-LVHPLLISINMLVV 488
            ::..|.:|:....|:.|.|||..:|.||.. |..|:.|..|.|.|
Mouse   446 KRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFV 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gcl	NP_724708.1	BTB_POZ_GCL	51..165	CDD:349614	43/114 (38%)
		BACK_GCL	166..245	CDD:350570	30/80 (38%)
Btbd35f21	NP_001257598.1	Nuclear localization signal. /evidence=ECO:0000255	33..39		4/5 (80%)
		BTB_POZ	80..190	CDD:453885	43/109 (39%)
		BACK	191..268	CDD:475122	30/80 (38%)