DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-SC1b and PGLYRP1

DIOPT Version :9

Sequence 1:	NP_001286209.1	Gene:	PGRP-SC1b / 35861	FlyBaseID:	FBgn0033327	Length:	185	Species:	Drosophila melanogaster
Sequence 2:	NP_005082.1	Gene:	PGLYRP1 / 8993	HGNCID:	8904	Length:	196	Species:	Homo sapiens

Alignment Length:	161	Identity:	79/161 - (49%)
Similarity:	99/161 - (61%)	Gaps:	1/161 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VVSKAEWGGRGAKWTVGLGNYLSYAIIHHTAGSYCETRAQCNAVLQSVQNYHMDSLGWPDIGYNF 88
            :|.:.||....::....|...|.|.::.|||||.|.|.|.|....::||:|||.:|||.|:||||
Human    33 IVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNF 97

  Fly    89 LIGGDGNVYEGRGWNNMGAHAAE-WNPYSIGISFLGNYNWDTLEPNMISAAQQLLNDAVNRGQLS 152
            |||.||.||||||||..|||:.. |||.||||||:|||......|..|.|||.||...|.:|.|.
Human    98 LIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALR 162

  Fly   153 SGYILYGHRQVSATECPGTHIWNEIRGWSHW 183
            |.|:|.|||.|..|..||..:::.|:.|.|:
Human   163 SNYVLKGHRDVQRTLSPGNQLYHLIQNWPHY 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-SC1b	NP_001286209.1	PGRP	22..163	CDD:128941	72/139 (52%)
PGLYRP1	NP_005082.1	PGRP	31..173	CDD:128941	72/139 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152330
Domainoid	1	1.000	147	1.000	Domainoid score	I4515
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4200
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46811
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	1	1.000	-	-		mtm8604
orthoMCL	1	0.900	-	-		OOG6_101717
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1649
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.760