Protein Alignment CG14743 and YDL206W

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_010075.1
• Gene: YDL206W / 851321
• SGDID: S000002365
• Length: 762
• Species: Saccharomyces cerevisiae
• Alignment Length: 709
• Identity: 138/709 - (19%)
• Similarity: 243/709 - (34%)
• Gaps: 233/709 - (32%)

  Fly    24 VSCLAVMHFSYLHRCEMATK--------IDDCKYI--TNFFNYYVMMYCSFKIDNKI--TEIVVM 76
            :.|:|.:.|.:....|..|:        .|...||  ...|.:.:::..:|..|.::  .|.:||
Yeast   123 MGCVATIQFQHDKSIETYTEESFDQNLSYDRSNYILDVGIFTFMLLVSGTFLADGRLYFWECIVM 187

  Fly    77 LLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRI--------NEYMA----------------- 116
            :   |.||  .|.:|. :.||..|.....||:..:        |.::.
Yeast   188 V---LTYC--CCAVYL-IKSYKYPCEINDALEREVEIKKTVLANNHITVPNRFTLTTTSDITSTD 246

  Fly   117 -GVVLV---GVANSTPDLLVNLSPVRMEGLT------FNIAMANALTIICLSGGAVCFIRPF-RM 170
             |:..|   |......|..::|.|.|:...:      ||..:.....:|...      ||.: |.
Yeast   247 DGIRYVRPLGDTQIDEDNAISLDPTRLPSKSLDNISRFNQGIPERRDLIRRR------IRGYLRS 305

  Fly   171 NGHSIFR-DLLFLLLIIELVRFFMN----------DTAL----------APWIKGAILLSIYP-- 212
            :.|...| .|..||.|.|....|.|          ||.|          .|.|:.. :.|:.|
Yeast   306 HYHGWVRMTLQDLLNIWEKQNLFNNTVKSLSLPSDDTHLFTKASLDEEGRPLIRKR-MNSLQPKD 369

  Fly   213 --IYLLI------NIVDLILLRYAIRKLRADIEVLRQSPSSREHDLILT---------------- 253
              .||.:      |.:|.     ||...:.:.:.....|:|    |.||
Yeast   370 FYKYLSLRNGENSNALDT-----AISAPQNEYQTYYNEPTS----LFLTVPQKKTSKKSLSCDRI 425

  Fly   254 EKIVRLNNLQQDDEIQILESKLYRKRTYNAGFFVTPKPLIHHKEVDVETNRRILHSKANPKNLFL 318
            ..:||.||:..:||....:..   ....|:...|....|:.::..|:..:|.:  |..:.|:...
Yeast   426 PNLVRSNNIILNDEATRTQES---TNALNSISDVIDNSLLQYERDDIILDRTL--SLCSTKSRTA 485

  Fly   319 FSEFLQAINPIDSEGWYLSGTCARI-----LQIL-KAPVTLMLHLVVP----LVDYQLVKHGWSK 373
            :..| |..|       ||:.....|     |.:| ..||:::|:|.:|    ..|:.|.    ..
Yeast   486 WHSF-QLYN-------YLTDVSLEIGFFEFLSLLVTTPVSIILYLSIPSEISQTDHDLP----LS 538

  Fly   374 MLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRTDIPPFYH 438
            .|..:|::.:|.::..|:..               ..:.|.|::::.:||:::..:|| ||..::
Yeast   539 YLQNIQLIASPIILNQLITN---------------NFSFWLLILSLVIAILLYFKTRT-IPNKFN 587

  Fly   439 SSY-----------C---ALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAAT 489
            |..           |   |:.|..|.:..||             .||:::.:.:.:|..:...:.
Yeast   588 SDIIFTVAFLLSLACLSKAVHIIVVTLTHWI-------------NVFNISETILGLTIFTWGNSI 639

  Fly   490 ADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVTIYIFLV 554
            .||::.....|.|..::|.||..|..:......||.:          |.:::.||.
Yeast   640 GDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFD----------GIMIMLGDK--------- 685

  Fly   555 ITITTTLWWCLTFNFVARRSAGLFMW---------------SLFVLFLVYTTAIEL-QW 597
                       |...|:.|.:.:.|.               .:.:.||::|..|.| .|
Yeast   686 -----------TGKIVSGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDW 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	43/209 (21%)
		Na_Ca_ex	450..591	CDD:279963	24/155 (15%)
YDL206W	NP_010075.1	ECM27	28..>223	CDD:223604	24/105 (23%)
		ECM27	<543..757	CDD:223604	44/250 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
TreeFam	0	0.000	Not matched by this tool.
	8	7.740