Protein Alignment CG14743 and slc24a3

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_012818629.1
• Gene: slc24a3 / 780317
• XenbaseID: XB-GENE-958238
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 626
• Identity: 114/626 - (18%)
• Similarity: 218/626 - (34%)
• Gaps: 213/626 - (34%)

  Fly    67 DNKITEIVVMLLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLL 131
            |.:...:::.:|||:...:.|.|:   .:.:|.|:|:..:.:::::|.:||...:...:|.|:|.
 Frog   143 DRRHGAVILHVLFAMYMFYALAIV---CDDFFVPSLEKISERLQLSEDVAGATFMAAGSSAPELF 204

  Fly   132 VNLSPVRME------GLTFNIAMANALTIICLSG---GAVCFIRPFRMNGHSIFRDLLFLLL-II 186
            .::..|.:.      |.....|:.|.|.||.:.|   |.|..     ::...:.||..:..| :|
 Frog   205 TSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVV-----LSAWCLLRDATYYTLSVI 264

  Fly   187 ELVRFFMNDTALAPWIKGAILLSIYPIYLLI-------------------NIVD----------- 221
            .|:.|..::.  ..|.:..||:.:|.:|:||                   |:.:
 Frog   265 ALIVFIYDEK--VSWWESLILVMMYAVYILIMKYNSSIHQFFERRKKSAANLANGLTANSELDDS 327

  Fly   222 ------LILLRYAIRKLRADIEVLRQSPSSREHDLILTEKIVRL---------NNLQQDDEIQIL 271
                  ::||.......:..:.::.:..|:..|.|..:|..:|:         ..|.....:.|.
 Frog   328 VHCEATMVLLNKGNCNRKTSVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLIN 392

  Fly   272 E-SKLYRKRTY-NAGFFVTPKPLIHH-----------KEVDVETNRRILHSKA-------NPKNL 316
            | .:|...|.| |....|:.|..|.|           .|.:..:|||...::|       |..|.
 Frog   393 ERQRLINSRAYVNGESEVSIKIPIKHAVENGTGPGNSTERNGNSNRRDDVAEAGNETENENEDNE 457

  Fly   317 FLFSEFLQAINPIDSEGWYL-----SGTCARILQILKAPVTLMLHLVVPLVDYQLVKHGWSKMLN 376
            ...::..:.....|::|.:.     ||...::..::..|:.|:|:..||               |
 Frog   458 NNENDEEEEEEEDDNDGPFTPFEVPSGNADKVKWMVTWPLCLLLYFTVP---------------N 507

  Fly   377 CLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRTDIPPFYHSSY 441
            |.:                 .::.:|:.|.....::|
 Frog   508 CAK-----------------PRWEKWFMVTFVSSSMW---------------------------- 527

  Fly   442 CALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKM 506
                   :....::..|    :::|||....:....|.|||.:...:..|.:|...:|:.|.|.|
 Frog   528 -------IAALSYVMVW----MVTIIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDM 581

  Fly   507 AFGAIIGGSVYSLAVNVGIELVLQK---------KLNSRGQV----------------------- 539
            |....||.:|:.:.:.:|:...||.         :|||||.:
 Frog   582 AVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIQLNSRGLIYSVALLLASLFVTVCGVRFNKWR 646

  Fly   540 ----------VLYGDDGVTIYIFLVITITTTLWWCLTFNFV 570
                      :|||       :||.::|.|..   ..|.||
 Frog   647 LDKKLGVACLLLYG-------VFLCLSILTEF---NVFTFV 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	30/143 (21%)
		PLN03151	<337..529	CDD:215604	31/191 (16%)
		Na_Ca_ex	450..591	CDD:426387	36/163 (22%)
slc24a3	XP_012818629.1	2A1904	<129..670	CDD:273344	110/614 (18%)