Protein Alignment CG14743 and slc24a5

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001025451.1
• Gene: slc24a5 / 570312
• ZFINID: ZDB-GENE-031210-1
• Length: 513
• Species: Danio rerio
• Alignment Length: 571
• Identity: 108/571 - (18%)
• Similarity: 196/571 - (34%)
• Gaps: 184/571 - (32%)

  Fly    73 IVVMLLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLL------ 131
            |..|||...|.|          :.||.|:|::.:.::.:::.:||...:...:|.|:|:
Zfish    88 IFYMLLSVSIVC----------DEYFLPSLEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGV 142

  Fly   132 ------VNLSPVRMEGLTFNIAMANALTIICLSGG----AVCFIRPFRMNGHSIFRDLLFLLLII 186
                  :.:|.: |....:|      |..||.:.|    ||     .|::...:|||.:...:.:
Zfish   143 FVTKGDIGVSTI-MGSAVYN------LLCICAACGLLSSAV-----GRLSCWPLFRDCVAYAISV 195

  Fly   187 ELVRFFMNDTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKLRADIEVL--RQSPSSREHD 249
            ..|...::|..:. |..||.||.:|.:|:.:...||.:..|.:::.......|  |...|..:..
Zfish   196 AAVIAIISDNRVY-WYDGACLLLVYGVYVAVLCFDLRISEYVMQRFSPCCWCLKPRDRDSGEQQP 259

  Fly   250 LILTEKIVRLNNLQQDDEIQILESKLYRKRTYNAGFFVTPKPLIHHKEVDVETNRRILHSKANPK 314
            |:         ....|..:::     .|:...::|.|.......|
Zfish   260 LV---------GWSDDSSLRV-----QRRSRNDSGIFQDDSGYSH-------------------- 290

  Fly   315 NLFLFSEFLQAINPIDSEGWYL----SGTCARILQILKAPVTLMLHLVVPLVDYQLVKHGWSKML 375
                .|..|..:|.|..|...:    .....|||.:|..||:.:|.:.||
Zfish   291 ----LSLSLHGLNEISDEHKSVFSMPDHDLKRILWVLSLPVSTLLFVSVP--------------- 336

  Fly   376 NCLQIVLTPFVIFALVETMLVHKYAEW--YYVPQFRM-AIWSLLVTMPLAIVVFLHSRTDIPPFY 437
            :|.:    ||                |  :|:..|.| |:|
Zfish   337 DCRR----PF----------------WKNFYMLTFLMSAVW------------------------ 357

  Fly   438 HSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHG 502
                       :..|.::..|    :::|:|....:..:.|.:|..:...:..|.:|...:|:.|
Zfish   358 -----------ISAFTYVLVW----MVTIVGETLGIPDTVMGMTLLAAGTSIPDTVASVMVAREG 407

  Fly   503 YGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVT----------IYIFLVITI 557
            ...||...|:|.:|:.: :.:|:...:|......|..|.....|:.          |::||.:.|
Zfish   408 KSDMAMSNIVGSNVFDM-LCLGLPWFIQTVFVDVGSPVEVNSSGLVFMSCTLLLSIIFLFLAVHI 471

  Fly   558 TTTLWWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIELQWVHGFQDNIQIR 608
            .   .|.|.:..      ||...:.::||...:...||    |...|..||
Zfish   472 N---GWKLNWKL------GLVCLACYILFATLSILYEL----GIIGNNPIR 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	35/158 (22%)
		Na_Ca_ex	450..591	CDD:279963	30/150 (20%)
slc24a5	NP_001025451.1	ECM27	81..497	CDD:223604	102/553 (18%)
		Na_Ca_ex	84..228	CDD:279963	37/162 (23%)
		Na_Ca_ex	346..497	CDD:279963	35/199 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810