Protein Alignment CG14743 and Slc24a1

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_064475.1
• Gene: Slc24a1 / 56814
• RGDID: 620080
• Length: 1181
• Species: Rattus norvegicus
• Alignment Length: 224
• Identity: 58/224 - (25%)
• Similarity: 101/224 - (45%)
• Gaps: 23/224 - (10%)

  Fly    64 FKIDNKITEIVVMLLFALIYCFF-LCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANST 127
            |.::::....||:.:|.:.|.|. |.|:   .:.||.|.|.:...|::|:|.:||...:....|.
  Rat   412 FSVEDRRQGWVVLHIFGMTYVFVALAIV---CDEYFVPALGVITDKLQISEDVAGATFMAAGGSA 473

  Fly   128 PDLLVNLSPVRME------GLTFNIAMANALTIICLSGGAVCFIRP-FRMNGHSIFRDLLFLLLI 185
            |:|..:|..|.:.      |.....|:.|.|.:|   |....|.|. ..:....:|||:.|.:|.
  Rat   474 PELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI---GTCALFSREILNLTWWPLFRDVSFYILD 535

  Fly   186 IELVRFFMNDTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKL--RADIEVLRQSPSSREH 248
            :.::..|..|:.:| |.:..:||..|.:|:.....:..:.|:...:|  |...:|:.....|:..
  Rat   536 LSMLIVFFLDSLIA-WWESLLLLLAYALYVFTMKWNKQIERWVKEQLSRRPVAKVMALGDLSKPS 599

  Fly   249 DLILTEKIVRLNNLQQDDEIQILESKLYR 277
            |..:.|      |.|||::...|.|.|.|
  Rat   600 DGAIEE------NEQQDNKKLKLPSVLTR 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	31/121 (26%)
		PLN03151	<337..529	CDD:215604
		Na_Ca_ex	450..591	CDD:426387
Slc24a1	NP_064475.1	2A1904	1..1181	CDD:273344	58/224 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	107..232
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..276
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..323
		Alpha-1	461..501		9/39 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..617		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	650..983
		14 X approximate tandem repeats	730..905
		Alpha-2	1061..1092