Protein Alignment CG14743 and slc24a6a

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_009289475.1
• Gene: slc24a6a / 561209
• ZFINID: ZDB-GENE-100922-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 626
• Identity: 118/626 - (18%)
• Similarity: 215/626 - (34%)
• Gaps: 200/626 - (31%)

  Fly    74 VVMLLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLLVNLSPVR 138
            :::.:|..:|.|:...:...|  :|.|:|:.....:.::|.:||...:...:|.|:|..:|..|.
Zfish   107 ILLHVFCAVYMFYALAIVCDV--FFVPSLEKICENLHLSEDVAGATFMAAGSSAPELFTSLIGVF 169

  Fly   139 ME------GLTFNIAMANALTIICLSGGAVCFI---RPFRMNGHSIFRDLLFLLL-IIELVRFFM 193
            :.      |.....|:.|.|.||     .||.|   :...:....:|||.:|.:| ::.|:....
Zfish   170 ITKGDLGVGTIVGSAVFNILVII-----GVCGIFAGQTITLTWWPLFRDSIFYILSVLALILIIY 229

  Fly   194 NDTALAPWIKGAILLSIYPIYLLI-----NIVDLILLRYAI-------RKLRADIEVLRQSPSSR 246
            ::..:  |.:..||:|:|.:|:||     .|...:..|:.|       ..||.|:.|...||..
Zfish   230 DEKVI--WWETIILISMYGVYILIMKFNSQIWGWVEQRFGIPGQPCLVSSLRRDVSVGEASPHC- 291

  Fly   247 EHDLILTEKIVRLNNLQQD------DEIQILESKLYRKRTYNAGFFVTP------------KPLI 293
            :..:||.:|  ..|...||      ||:..|....:.....:....:||            :.||
Zfish   292 DTSMILLKK--GQNAGGQDSPVVMVDELMSLHPHQFSFSEASLRVMITPHFSPRTRLSMAGRMLI 354

  Fly   294 HHKEVDVETNRRILHSKANPKNLFLFSEFLQAINPIDSEG------------------WYL---- 336
            ..::       |::.::                :|.||.|                  |.|
Zfish   355 TERQ-------RLIRNR----------------SPGDSSGSGAGDTPGQDGPGMEAVPWGLENGG 396

  Fly   337 -----------------SGTCARILQILKA------------------PVTLMLHLVVPLVDYQL 366
                             .|...|:..|...                  |.|      ||...::.
Zfish   397 ALESETQPLEEPRRRSQGGELERVADIEDTQPKDDEEDEEEADEEPFRPFT------VPEGRWEQ 455

  Fly   367 VKHGWSKMLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRT 431
            .|..:|..|:||        ::..|...::.::..|:.|......:|
Zfish   456 AKWMFSWPLSCL--------LYYTVPNCVLPRWERWFMVTFVASTLW------------------ 494

  Fly   432 DIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYA 496
                             :.:|.::..|    :::||....|:....|.|||.:...:..|.:|..
Zfish   495 -----------------IAVFSYLMVW----MVTIISFTLDIPDVVMGITFLAAGTSVPDCMASL 538

  Fly   497 HLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVTIY--------IFL 553
            .:|:.|.|.||....||.:::.:.:.:|....|:..:...|..|.....|: :|        :||
Zfish   539 IVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLVVDYGSTVSINSKGL-VYSVILLLASVFL 602

  Fly   554 VITITTTLWWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIE 594
            .:.......|.|.      |..||.:..|:.:||:.:...|
Zfish   603 TVLSVHLNHWRLD------RRLGLGLMFLYAIFLLCSICFE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	38/157 (24%)
		Na_Ca_ex	450..591	CDD:279963	34/148 (23%)
slc24a6a	XP_009289475.1	Na_Ca_ex	<85..637	CDD:332332	117/624 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810