DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14743 and slc8b1

DIOPT Version :9

Sequence 1:	NP_610408.2	Gene:	CG14743 / 35860	FlyBaseID:	FBgn0033326	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_021333605.1	Gene:	slc8b1 / 560601	ZFINID:	ZDB-GENE-130530-900	Length:	301	Species:	Danio rerio

Alignment Length:	242	Identity:	61/242 - (25%)
Similarity:	97/242 - (40%)	Gaps:	28/242 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 CLAVMHFSYLHRCEMATKIDDCKYITNFFNYYVMMYCSFK---IDNKITEIVVMLLFALIYCFFL 87
            |..||:.|...|||......||.....|..|..:.:|.|.   :...||..|:.|||..:
Zfish    55 CDVVMNVSASQRCEYVKNTPDCASDEGFIKYPFVTFCLFTPSLLPLAITIYVIWLLFLFL----- 114

  Fly    88 CILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDL---LVNLSPVRMEGLTFNIAMA 149
             :|....:.:|.|.|...|..:|:...:|||..:.:.|..||:   :...|..:..||.......
Zfish   115 -VLGLIASDFFCPNLSAIASTLRLTHNVAGVTFLALGNGAPDVFSAMAAFSHPQTAGLAIGALFG 178

  Fly   150 NALTIICLSGGAVCFIRPFRMNGHSIFRDLLFLLLIIELVRFFMNDTALAPWIKGAILLSIYPIY 214
            ..:.:..:..|:|..::||.:......||::|.:..:     |...|.|   .||.|.|.....|
Zfish   179 AGIFVTTVVAGSVALVKPFTVASRPFLRDVIFYMAAV-----FWTFTVL---YKGHISLGESVGY 235

  Fly   215 L---LINIVDLILLRYAIRKLRADIEVLRQSP--SSREHDLILTEKI 256
            |   :..:..:||..|...:.:   ..|.:||  |.||...||:..:
Zfish   236 LGMYIAYVFTVILSSYIYNRQK---HQLTESPQSSDREQGGILSSDL 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	34/148 (23%)
CG14743	NP_610408.2	Na_Ca_ex	450..591	CDD:279963
slc8b1	XP_021333605.1	Na_Ca_ex	66..>246	CDD:332332	46/193 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41602
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		otm26516
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.750