Protein Alignment CG14743 and slc24a3

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_685302.4
• Gene: slc24a3 / 557196
• ZFINID: ZDB-GENE-090312-67
• Length: 660
• Species: Danio rerio
• Alignment Length: 627
• Identity: 112/627 - (17%)
• Similarity: 212/627 - (33%)
• Gaps: 192/627 - (30%)

  Fly    64 FKIDNKITEIVVMLLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTP 128
            |....::...|.:.:...:|.|:...|.  .:.||.|:|:....::.::|.:||...:...:|.|
Zfish   115 FTQQERLEGAVALHVLCAMYMFYALALV--CDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAP 177

  Fly   129 DLLVNLSPVRME------GLTFNIAMANALTIICLSGGAVCFI---RPFRMNGHSIFRDLLFLLL 184
            :|..::..|.:.      |.....|:.|   |:|:.|  ||.|   :..|::..::.||..:..:
Zfish   178 ELFTSVIGVFITKGDVGVGTIVGSAVFN---ILCIIG--VCGIFTAQAVRLSCWTLMRDSTYYTI 237

  Fly   185 IIELVRFFMNDTALAPWIKGAILLSIYPIYLLI-----------------------------NIV 220
            .:..:..|:.|..:. |.:..||:.:|.:|:||                             :|.
Zfish   238 AVATLIVFIYDEKVT-WWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTDID 301

  Fly   221 D-----LILLRYAIRKLRADIEVLRQSPSSREHDLILTEKIVRL---------NNLQQDDEIQIL 271
            |     ::||:.|....:..:.::.:..|:..|.|..:|..:|:         ..|.....:.|.
Zfish   302 DGCDATVVLLKKANFHRKPSVLMVDELLSAYPHQLTFSEAGMRIMITSHFSPRTRLTMASRMLIT 366

  Fly   272 E-SKLYRKRTYNAGFFVTPK---------PLI------------HHKE--------VDVETNRRI 306
            | .:|...|..|....||.|         .|.            ||.:        .|.|.....
Zfish   367 ERQRLINSRFSNGDSEVTVKMPGKRGVENGLAGPDRGLNGRKGGHHDDDRGGAEAGTDTENENED 431

  Fly   307 LHSKANPKNLFLFSEFLQAINPIDSEGWYLSGTCA-----RILQILKAPVTLMLHLVVPLVDYQL 366
            ..:..|.:         :.....::||.|:...|.     ::..:|..|::::|...||    ..
Zfish   432 NENNENDE---------EEEEEDENEGPYVPFRCPGGGINKLKWLLAWPLSMLLFFTVP----NS 483

  Fly   367 VKHGWSKMLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRT 431
            ....|.:                            ||.|......||
Zfish   484 ANPRWER----------------------------WYMVSFISSTIW------------------ 502

  Fly   432 DIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYA 496
                             :..|.:|..|    ::::||....:....|.|||.:...:..|.:|..
Zfish   503 -----------------IAFFSYIMVW----MVTVIGYTMGIPDVIMGITFLAAGTSVPDCLASL 546

  Fly   497 HLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQK---------KLNSRGQVVLYGDDGVTIYIF 552
            .:|:.|.|.||....||.:|:.:.:.:|:...||.         .|||:|.:...|        .
Zfish   547 IVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTLAINYGSTIHLNSKGLIFSVG--------L 603

  Fly   553 LVITITTTLWWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIE 594
            |:.::..|:......|:...:..|.....::.:||.::..||
Zfish   604 LLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILIE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	29/152 (19%)
		PLN03151	<337..529	CDD:215604	32/196 (16%)
		Na_Ca_ex	450..591	CDD:426387	33/149 (22%)
slc24a3	XP_685302.4	2A1904	<96..650	CDD:273344	112/627 (18%)