DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14743 and slc8b1

DIOPT Version :9

Sequence 1:	NP_610408.2	Gene:	CG14743 / 35860	FlyBaseID:	FBgn0033326	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001017082.1	Gene:	slc8b1 / 549836	XenbaseID:	XB-GENE-957176	Length:	238	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	53/229 - (23%)
Similarity:	91/229 - (39%)	Gaps:	22/229 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLKYLINTSP--YSFLNESDFMQN-VSCLAVMHFSYLHRCEMATKIDDCKYITNFFNYYVMMYCS 63
            |.::||...|  |||    :.:|| ..|..|.......||.......||.....:.||....:||
Frog    19 SAEFLIGMEPLNYSF----NSVQNKADCQEVGKLDASLRCNFTRTTPDCSVGDGYINYLDGAFCS 79

  Fly    64 FKIDNKITEIVVMLLFA----LIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVA 124
            |     :..:..:.:|.    |:|.|.  ||......:|.|.|...:..:|::..:|||..:...
Frog    80 F-----LPSLFPLAIFLYTLWLLYLFI--ILAVTAEKFFCPNLSAISRILRLSHNVAGVTFLAFG 137

  Fly   125 NSTPDL---LVNLSPVRMEGLTFNIAMANALTIICLSGGAVCFIRPFRMNGHSIFRDLLFLLLII 186
            |..||:   :...|..|..||.........:.:..:..|.:..::||........||::|.:..|
Frog   138 NGAPDVFSAVAAFSDSRTAGLAIGALFGAGVFVTTVVAGGITIVKPFTAASRPFLRDIVFYISAI 202

  Fly   187 ELVRFFMNDTALAPWIKGAILLSIYPIYLLINIV 220
            .|. ||:.........:..:.|.:|.:|:.:.::
Frog   203 FLT-FFILYQGFVTLAEALVYLLLYLVYVFVVVI 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	33/149 (22%)
CG14743	NP_610408.2	Na_Ca_ex	450..591	CDD:279963
slc8b1	NP_001017082.1	Na_Ca_ex	94..219	CDD:279963	29/127 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I8955
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41602
Inparanoid	1	1.050	205	1.000	Inparanoid score	I3626
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12266
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160