Protein Alignment CG14743 and Slc24a5

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_778199.2
• Gene: Slc24a5 / 317750
• MGIID: 2677271
• Length: 501
• Species: Mus musculus
• Alignment Length: 569
• Identity: 105/569 - (18%)
• Similarity: 204/569 - (35%)
• Gaps: 173/569 - (30%)

  Fly    73 IVVMLLFALIYCFFLCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLL------ 131
            ||:..|..|..|..:.|:   .:.||.|:|:|.:..:.:::.:||...:...:|.|:|:
Mouse    69 IVIYFLIILYMCMAISIV---CDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGV 130

  Fly   132 ------VNLSPVRMEGLTFNIAMANALTIICLSGGAV--------CFIRPFRMNGHSIFRDLLFL 182
                  :.:|.:      ...|:.|.|. ||.:.|.:        |:         .:|||....
Mouse   131 FITKGDIGISTI------LGSAIYNLLG-ICAACGLLSNMVSTLSCW---------PLFRDCAVY 179

  Fly   183 LLIIELVRFFMNDTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKLRADIEVLRQSPSSRE 247
            .:.:..|...:.|..:. |.:||.||.||.:|:|:...|..:.|:.::........|.::
Mouse   180 AVSVGAVFGIIFDNRIY-WYEGAGLLLIYGLYVLLLCFDTTISRHVMKTCSPCCPCLARA----- 238

  Fly   248 HDLILTEKIVRLNNLQQDDEIQILESKLYRKRTYNAGFFVTPKPLIHHKEVDVETNRRILHS--- 309
                :.|:|.:...|..:||.|:.   :.|:...::|.|....   .:.::.:.     ||.
Mouse   239 ----MEERIEQQTLLGWEDESQLF---IRRQSRTDSGIFQEDS---GYSQLSLS-----LHGLSQ 288

  Fly   310 -KANPKNLFLFSEFLQAINPIDSEGWYLSGTCARILQILKAPVTLMLHLVVPLVDYQLVKHGWSK 373
             ..:|.::|...|                ....||..:|..|:..:|.|..|
Mouse   289 VSEDPPSVFSMPE----------------ADLRRIFWVLSLPIITLLALTTP------------- 324

  Fly   374 MLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRM-AIWSLLVTMPLAIVVFLHSRTDIPPFY 437
              :|.:                  |:.:.|:|..|.| |:|
Mouse   325 --DCRR------------------KFWKNYFVITFFMSALW------------------------ 345

  Fly   438 HSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHG 502
                       :..|.:|..|    ::::.|....:..:.|.:|..:...:..|.:....:|:.|
Mouse   346 -----------ISAFTYILVW----MVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKG 395

  Fly   503 YGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVTIYIFLVITITTTLWWCLTF 567
            .|.||...|:|.:|:.: :.:|:...::....:....:.....|:| ||.:.:.|:      :.|
Mouse   396 KGDMAISNIVGSNVFDM-LCLGLPWFIKTAFTNASAPIEVNSKGLT-YITISLNIS------ILF 452

  Fly   568 NFVARRSAGLFMWSL--------FVLFLVYTTAIELQWVHGFQDNIQIR 608
            .|:|....|   |.|        .||:|...| :.:.:..|...|.:||
Mouse   453 LFLAVHFNG---WKLDRKLGVVCLVLYLGLAT-LSVLYEIGIIGNNRIR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	36/162 (22%)
		Na_Ca_ex	450..591	CDD:279963	30/148 (20%)
Slc24a5	NP_778199.2	Na_Ca_ex	72..216	CDD:279963	36/163 (22%)
		TIGR00367	77..477	CDD:273039	96/538 (18%)
		Na_Ca_ex	334..485	CDD:279963	37/201 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810