Protein Alignment CG14743 and Slc24a4

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001388274.1
• Gene: Slc24a4 / 314396
• RGDID: 1305926
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 125/600 - (20%)
• Similarity: 232/600 - (38%)
• Gaps: 172/600 - (28%)

  Fly    74 VVMLLFALIYCFF-LCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLLVNLSPV 137
            |::.:...:|.|: |.|:   .:.:|.|:|:....|:.::|.:||...:...:|||:|..::..|
  Rat   100 VLLHILGALYMFYALAIV---CDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGV 161

  Fly   138 RME------GLTFNIAMANALTIICLSGGAVCFI---RPFRMNGHSIFRD-LLFLLLIIELVRFF 192
            .:.      |.....|:.|   |:|:.|  ||.:   :..|:...::.|| :.:.|.:|.|:.|.
  Rat   162 FITHGDVGVGTIVGSAVFN---ILCIIG--VCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFI 221

  Fly   193 MNDTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKLRA---------------DI------ 236
            .::..:  |.:|.||:.:|..|:||...::.:..:...|.::               |:
  Rat   222 YDEEIV--WWEGLILIILYVFYILIMKYNMKMQTFFTTKQKSIANGNPVSNELEDGNDLYDGSFD 284

  Fly   237 -------------------------EVLRQSPSSREHD-----LILTEKIVRLNNLQQDDEIQIL 271
                                     |:|..||......     :::|.|......|:....|.|.
  Rat   285 DPSVPLLGQVKEKPPYGKSPVVMVDEILSSSPPKFTFPEAGLRIMITNKFGPRTRLRMASRIIIN 349

  Fly   272 ESKLYRKRTYNAGFFVTPKPLIHHKEVDVETNRRILHSKANPKNLFLFSEFLQAINPIDSEGWYL 336
            |    |:|..|:...|..|||.:.:..::|.....:.:..:|:                 :|
  Rat   350 E----RQRLINSANGVNSKPLQNGRHENMENGNVPVENPEDPQ-----------------QG--- 390

  Fly   337 SGTCARILQILKAPVTLMLHLVVPLVDYQLVKHGWSKMLNCLQIVLTPFVIFALVETMLVHKYAE 401
                    |..:.|..      .|..:.:.|:          .:.|:|   |::.|..  ...|:
  Rat   391 --------QEQQPPPQ------PPPPEPESVE----------TVFLSP---FSMPEAK--GDKAK 426

  Fly   402 WYYVPQFRMAIWSLL----VTMPLAIVVFLHSRTDIPPFYHSSYCALTISTVIIFFWICAWEMDA 462
            |.:.       |.|:    ||:|..      |:.....|:..::...|: .:.:|.::..|
  Rat   427 WVFT-------WPLIFLLCVTIPNC------SKPRWEKFFMVTFITATL-WIAVFSYLMVW---- 473

  Fly   463 LISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIEL 527
            |::|||....:....|.|||.:...:..|.:|...:|:.|.|.||....||.:|:.:.|.:||..
  Rat   474 LVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPW 538

  Fly   528 VLQK---------KLNSRG----QVVLYGDDGVTIYIFLVITITTTLWWCLTFNFVARRSAGLFM 579
            .||.         |:||||    .|:|.|...:|:   |.|.:..   |.|.      |..|:::
  Rat   539 GLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTV---LGIHLNK---WRLD------RKLGIYV 591

  Fly   580 WSLFVLFLVYTTAIE 594
            ..|:.:||.::..||
  Rat   592 LVLYAVFLCFSIMIE 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	32/124 (26%)
		PLN03151	<337..529	CDD:215604	41/195 (21%)
		Na_Ca_ex	450..591	CDD:426387	43/153 (28%)
Slc24a4	NP_001388274.1	2A1904	<80..606	CDD:273344	123/598 (21%)