Protein Alignment CG14743 and SPAC3A12.06c

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_593332.1
• Gene: SPAC3A12.06c / 2543183
• PomBaseID: SPAC3A12.06c
• Length: 743
• Species: Schizosaccharomyces pombe
• Alignment Length: 750
• Identity: 148/750 - (19%)
• Similarity: 276/750 - (36%)
• Gaps: 235/750 - (31%)

  Fly    15 LNESDFMQNVSCLAVMHFSYLHRCEMATKIDDCK-YITNFFNYYVMMYCSFKIDNKITEIVVMLL 78
            ||:|:....::|..:.:.:..::|..|...  || ..:.||:|....:|:.   |.:...|:.::
pombe    56 LNDSNDQILLTCNDIKNITPANQCRFAKAY--CKGEASGFFDYVEFYFCTI---NSLRFPVLSII 115

  Fly    79 FALIYCFFLCILYEGVNS--YFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLLVNLSPVRME- 140
            ...:...|:.|   |:::  :|:..|...:..:::.:.:.||..:.:.|.:||:|...:.||:.
pombe   116 VGWLIFLFITI---GISASDFFSTNLVTISWLLQLPDSVVGVTFLALGNGSPDILSTFAAVRVNS 177

  Fly   141 -GLTFNIAMANALTIICLSGGAVCFIRPFRMNGHSIFRDLLFLL-LIIELVRFFMNDTALAPWIK 203
             |:.....:.:|..|:.:..|:||.|:||::......||:.||. .|:.::.|.::|.:|:.| :
pombe   178 GGMAIGELLGSAFFIVAIVAGSVCLIKPFKIPRRHFLRDVAFLTGTILLVIMFVLHDGSLSIW-Q 241

  Fly   204 GAILLSIYPIYLL------------------------------INIVD----------------L 222
            ..:::..|.:|:|                              :|..|                .
pombe   242 SLVMILYYLLYVLFVFFSGSSGVSVVITDENYLPVSLPVYSPVLNSFDDSDSYSSTDSELSEEAF 306

  Fly   223 ILLRYAIRKLRADIEVLRQSPS--------SREHDLI---------------------------- 251
            :|...|.||.:....:....||        |..||.|
pombe   307 LLPAQASRKTQKIHYINDNDPSNSYSSYQHSHVHDFIHKNNTHSNRVLSQSSGPIVRPSLLAALD 371

  Fly   252 ------------------------LTEKIVRLNNLQQD-----------------------DEIQ 269
                                    ||...:.:.:.|.|                       :.:|
pombe   372 FRSSNEEQHPGLRSLDPLNIQDGDLTMHPMHIRHSQSDFYPSGINTPVSGINYPNLGFSANNSVQ 436

  Fly   270 ILESKLYRKRTYNAGFFVTPKPLIHHKEVDVETNRRILHSKANPKNLFLFSEFLQAINPIDSEGW 334
            .|.|:::|..|:....|..|.|                         .|.|.....:.....:.|
pombe   437 SLVSEIFRHPTHTDEDFPLPSP-------------------------SLSSLLFPTLRNFAKKSW 476

  Fly   335 YLSGTCARILQILKAPVTLMLHLVVPL-------VD--YQL-------VKHGWSKMLNCLQIVLT 383
            |     .:::.:|..|..|:..|.:|:       ||  |.:       .|..||:.|..||.|..
pombe   477 Y-----EKLMDVLAVPSVLIFTLALPVYQCPRLAVDPIYHMDVSNCNPSKPTWSRKLRLLQCVFV 536

  Fly   384 P--FVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRTDIPPFY--HSSYCAL 444
            |  ||.|::.....::.||        ..:::|:|....|    :.::..:.||.:  ..|:
pombe   537 PFAFVTFSITGGNRLYIYA--------ASSVFSILCITAL----YYYTDEEKPPKFLPWVSF--- 586

  Fly   445 TISTVIIFFWI--CAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMA 507
             |..|:...||  .|.|:..::..:||:|:|..|.:.:|..:...:.:||||...:|:.|:.:||
pombe   587 -IGFVLGIIWISTIANEVVGILRALGVIFNLNESILGLTVFAAGNSLSDLIADIMIARSGFPEMA 650

  Fly   508 FGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGV---------TIYIFLVITITTTLWW 563
            .|.:.||...::.:.:||........|       :|:|.|         |.| ||:..:...|.:
pombe   651 MGGVFGGPTLNILIGIGISSFYSSISN-------HGNDSVIEIPHSLSITAY-FLLACLLLLLIY 707

  Fly   564 CLTFNFVARRSAGLFMWSLFVLFLVYTT---AIEL 595
            .....|...|..||.   ||:|::|.|:   .:||
pombe   708 VPLNRFRVNRVLGLL---LFILYIVGTSTNIVVEL 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	35/177 (20%)
		Na_Ca_ex	450..591	CDD:279963	40/151 (26%)
SPAC3A12.06c	NP_593332.1	PLN03151	76..729	CDD:215604	140/718 (19%)
		Na_Ca_ex	118..258	CDD:279963	34/143 (24%)
		Na_Ca_ex	584..729	CDD:279963	42/159 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	73	1.000	Domainoid score	I2545
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I1261
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
TreeFam	1	0.960	-	-
	10	9.820