Protein Alignment CG14743 and ncx-9

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_504342.2
• Gene: ncx-9 / 182576
• WormBaseID: WBGene00003574
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 133/697 - (19%)
• Similarity: 270/697 - (38%)
• Gaps: 141/697 - (20%)

  Fly     8 NTSPY-SFLNESDFMQNVSCLAVMHFSYLHRCE-MATKIDDCK---YITNFFNYYVMMYCSFKID 67
            |.|.| .|..:.:...:..||....::...:|| :....|.|:   |:|  :::||.  |.:.|.
 Worm    38 NFSIYDGFPFDEEMCSSEECLIDKSWTSEEKCEYIKCNQDSCEGGGYLT--WSHYVK--CQYNIG 98

  Fly    68 NKITEIVVMLLFALIYCFFLCILYEGV-NSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLL 131
            .:    |::::..::|...|.::...: :.:|.|.:......:|::|.:|||..:...|..||:.
 Worm    99 VR----VILIILGILYLIILFVIMSSIADDFFCPAISGIVSHLRMSESIAGVTFLAFGNGAPDVF 159

  Fly   132 VNLS-----PVRMEGLTFNIAMANALTIICLSGGAVCFIRPFRMNGHSIFRDLLFLLLIIELVRF 191
            .::|     |.....|........::.:..:....:.|.:.|::......|||:|.:..:..:.|
 Worm   160 SSISSVLTTPKPKADLALGDLFGTSIFVTTVVLAIIIFTKSFKVAIIPTLRDLIFYMTTLAFIVF 224

  Fly   192 -FMNDTALAPWIKGAILLSIYPIYLLINIVDLILL--------RYAIRKLRADIEVLRQSPSSRE 247
             |:....:..|:. |..|.||.:|    :|.:|:|        :..::|...::|.....|||..
 Worm   225 CFLKFDKIEVWMP-ATFLGIYGVY----VVTVIILGIYRTHRKKRNLKKKNKELEDFLSRPSSAA 284

  Fly   248 HD------LILTEKIVRLN-------------------NLQQDDEIQILESKLYRKRTYNAGF-- 285
            ..      :.|.|:.:.::                   ||::.......::|..::...|.||
 Worm   285 STTPIFGAMKLKEETISVSALFHFMIGYSQFIKNLTRANLKRTTNNNNNDNKNEKRGIVNLGFSE 349

  Fly   286 -FVTP---KPLIHHKEVDVETNRRILHSKA-----------------------NPKNLFLFSEFL 323
             :..|   |.....|:...||:...|.|.|                       :...:.|.:..:
 Worm   350 PYSIPSERKISTIFKQNTFETDLESLESLADLDGSDDEGREEKFGYAHHTVFTSHDQISLVASEI 414

  Fly   324 QAINPIDSEGW--------YLSGTCAR-----------ILQILKAPVTLMLHLVVPLVDYQLVKH 369
            :.|.......|        :|....:|           |:.::|........|.||..:.
 Worm   415 EEIEITTWRSWDWVWDLFNHLKSWPSRDEFSEMNIFIKIVTVIKVVPVFFFKLTVPSNEM----- 474

  Fly   370 GWSK---MLNCLQIVLTPFVIFALVETMLVHKY----AEWYYVPQFRMAIWSLLVTMPLAIVVFL 427
            .|.|   :|:|...:  .|.:|: ::.:.:..:    ..|.|...|     |.::.|   :.::.
 Worm   475 SWCKPLFILHCFASI--QFALFS-IQIITLKPFDGSPGLWLYGLGF-----SAILAM---VAMYF 528

  Fly   428 HSRTDIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADL 492
            ...:....:|...|..|.....|.:.:..:.|:.:::::||||..|:...:.:|..:.|....|:
 Worm   529 LPLSKEQKYYKEIYSYLGFLMSIAWIYATSNEIVSVVTMIGVVTGLSMELLGLTIMAWSNCIGDI 593

  Fly   493 IAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVTIY----IFL 553
            :|...:.|.||.|||..|.|||.:::|.:..|:...:........::::.     .:|    :||
 Worm   594 VADIAVVKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIAAAQGKEMELLIN-----PVYRLLMLFL 653

  Fly   554 VITITTTLWWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIE---LQW 597
            .|::.||........|..||...:.:..:||:||::....|   |:|
 Worm   654 GISLVTTFVALFIQRFTVRRPHAVLLIFIFVVFLIFICLAEFHVLEW 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	29/149 (19%)
		Na_Ca_ex	450..591	CDD:279963	36/144 (25%)
ncx-9	NP_504342.2	PLN03151	68..689	CDD:215604	124/654 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165698
Domainoid	1	1.000	75	1.000	Domainoid score	I5893
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41602
Inparanoid	1	1.050	162	1.000	Inparanoid score	I2840
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D257493at33208
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm4752
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770