Protein Alignment CG14743 and ncx-4

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001040663.1
• Gene: ncx-4 / 172834
• WormBaseID: WBGene00003569
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 110/580 - (18%)
• Similarity: 212/580 - (36%)
• Gaps: 136/580 - (23%)

  Fly    64 FKIDNKITEIVVMLLFALIYCFF-LCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANST 127
            |.::.:....||:.:..|||.|. |.|:   .:.:|.|:|.:...|:.:::.:||...:....|.
 Worm    92 FSLEQRQNGFVVLHMCGLIYMFVSLAIV---CDEFFVPSLDVLTEKLSLSDDVAGATFMAAGGSA 153

  Fly   128 PDLLVNLSPVRME-----------GLTFNIAMANALTIICLSGGAVCFIRP-FRMNGHSIFRDL- 179
            |:...::..|.:.           ..|||        |:|:......|.:. ..:....:|||:
 Worm   154 PEFFTSVIGVFIAQNNVGIGTIVGSATFN--------ILCVLAFCTLFSKSILDLTWWPLFRDVS 210

  Fly   180 LFLLLIIELVRFFMNDTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKLRADIE-VLRQSP 243
            :::|.:..||.|||::....|  :...:.|||.:|.            .:.|....:| ::::..
 Worm   211 IYMLALAMLVFFFMDEMITFP--EALAMFSIYIVYC------------TVMKFNGQLEQLVKKGS 261

  Fly   244 SSREHDLILTEKI---VRLNNLQQDDEIQILESKLYRKRT--------------YNAGFFVTPKP 291
            .|.|.....|:|:   |..|| ..:|..|:..|:|.|:.:              :..|.......
 Worm   262 DSEEASAHETQKLAADVPHNN-NNNDLAQLEGSELRRRSSARRQSVPILHSGTMFRNGIMQLMNQ 325

  Fly   292 LIHHKEVDVETNRRILHSKANPKNLFLFSEFLQAINPIDSEGWYLSGTCARILQILKAPVTLMLH 356
            .:.....|.|.:    .|..:..|:.:.|..:..:|...|.....|.....|..:|:......|.
 Worm   326 TLEQLPEDSEED----DSSRSRSNVNIESHDMHRLNVNQSMPDRRSSQIEEIKSLLEEQEEKPLD 386

  Fly   357 LVVPLVDYQLVKHGWSKMLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPL 421
            :..|        ..|.|.|.  .::|.|.||            ..|..:|..|.:
 Worm   387 MTWP--------ETWVKRLT--YVLLAPVVI------------PMWVTIPDVRKS---------- 419

  Fly   422 AIVVFLHSRTDIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVS 486
                  |:|...|..:     .::|..:..|.::..|    ..:.||..|.:....:.:|..:..
 Worm   420 ------HNRGLYPATF-----IISILWIAFFSYLMVW----WANTIGETFVIPTEIIGLTILAAG 469

  Fly   487 AATADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVL---------------QKKLNSR 536
            .:..|||....:|:.|.|.||..:.:|.:::.:.|.:.|..:|               ...::|:
 Worm   470 TSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLLYFLIEYIKHPNEPLSPISVSSK 534

  Fly   537 GQVVLYGDDGVTIYIFLVITITTTL--WWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIE 594
            |.:...|    .::|.|::.:....  .|.:...|      |:.|...:|.|.|::.::|
 Worm   535 GLLCSVG----MLFIMLIVLVFAIFLSGWKMNKIF------GILMIVSYVFFCVFSVSLE 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	26/127 (20%)
		PLN03151	<337..529	CDD:215604	36/191 (19%)
		Na_Ca_ex	450..591	CDD:426387	30/157 (19%)
ncx-4	NP_001040663.1	2A1904	<48..594	CDD:273344	110/580 (19%)