Protein Alignment CG14743 and slc24a5

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_002936612.2
• Gene: slc24a5 / 100490024
• XenbaseID: XB-GENE-853669
• Length: 546
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 107/542 - (19%)
• Similarity: 200/542 - (36%)
• Gaps: 158/542 - (29%)

  Fly    86 FLCILYEGV------NSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLL------------V 132
            ||.|||..:      .|||.|:|::.:.::.:::.:||...:.:.:|.|:.:            :
 Frog   118 FLIILYMFLAVAIVCESYFIPSLEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDI 182

  Fly   133 NLSPVRMEGLTFNIAMANALTI---ICLSGGAVCFIRPFRMNGHSIFRDLLFLLLIIELVRFFMN 194
            .:|.:      ...|:.|.|.|   .||...:|.     |:....:|||.:...:.:..|.....
 Frog   183 GVSTI------VGSAVYNLLGICAACCLLSLSVS-----RLTCWPLFRDCVAYAISVAAVIAITF 236

  Fly   195 DTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKLRADIEVLRQS-PSSREHDLILTEKIVR 258
            |..:. |.:.|.|:.||.||::....|:.:.:|.:|:........|:: ..:.||:.:|..|
 Frog   237 DNRIY-WYESASLILIYGIYIVTMCFDIRINQYIMRRFSPCCTCCREAMVGNTEHEPLLGWK--- 297

  Fly   259 LNNLQQDDEIQILESKLYRKRTYNAGFFVTPKPLIHHKEVDVETNRRILHSKANPKNLFLFSEFL 323
                  :|.:.::.    |....::|.|....   .:.::.:..: .:..|..||.::|...|
 Frog   298 ------EDSLPVIR----RHSRSDSGIFQEES---DYSQLSISLS-GLKESSNNPPSVFTMPE-- 346

  Fly   324 QAINPIDSEGWYLSGTCARILQILKAPVTLMLHLVVPLVDYQLVKHGWSKMLNCLQIVLTPFVIF 388
                          ....||:.:|..|:..:|:|.||               :|
 Frog   347 --------------NDLKRIIWVLSLPIITLLYLTVP---------------DC----------- 371

  Fly   389 ALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRTDIPPFYHSSYCALTISTVIIFF 453
                                |...|.     .|.|:.||.|             |:.||.|.
 Frog   372 --------------------RRKRWK-----NLFILTFLMS-------------AVWISAVT--- 395

  Fly   454 WICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMAFGAIIGGSVYS 518
            :|..|    :::::|....:..:.|.:|..:...:..|.:|...:|:.|.|.||...|:|.:|:.
 Frog   396 YILVW----MVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFD 456

  Fly   519 LAVNVGIELVLQKKLNSRGQVVLYGDDGVTIYIFLVITITTTLWWCLTFNFVARRSAG------- 576
            : :.:|:...::.....|...|.....|:|.       .|.:|.:.:.|.|||....|
 Frog   457 M-LCLGVPWFIKTVFVDRSAPVEVNSSGITY-------TTISLLFSILFIFVAIHLNGWKLDKKL 513

  Fly   577 ----LFMWSLFV-LFLVYTTAI 593
                |.|:.||| |.::|...|
 Frog   514 GVMCLLMYLLFVTLSILYELGI 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	25/129 (19%)
		PLN03151	<337..529	CDD:215604	36/191 (19%)
		Na_Ca_ex	450..591	CDD:426387	34/152 (22%)
slc24a5	XP_002936612.2	2A1904	<95..>274	CDD:273344	38/167 (23%)
		2A1904	<332..536	CDD:273344	60/299 (20%)