Protein Alignment CG14743 and slc24a4

DIOPT Version :10

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_002933272.2
• Gene: slc24a4 / 100489343
• XenbaseID: XB-GENE-478288
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 118/586 - (20%)
• Similarity: 219/586 - (37%)
• Gaps: 141/586 - (24%)

  Fly    64 FKIDNKITEIVVMLLFALIYCFF-LCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANST 127
            |.|..:....|:..:|..:|.|: |.|:   .:.:|.|:|:....|:.::|.:||...:...:||
 Frog    97 FSIKERQRGAVLFHIFCALYMFYALAIV---CDDFFVPSLEKICEKLHLSEDVAGATFMAAGSST 158

  Fly   128 PDLLVNLSPVRME------GLTFNIAMANALTIICLSGGAVCFI---RPFRMNGHSIFRDLLFLL 183
            |:|..::..|.:.      |.....|:.|   |:|:.|  ||.:   :..|:...|:|||.::.:
 Frog   159 PELFASVIGVFITHGDVGVGTIVGSAVFN---ILCIIG--VCGVFAGQVVRLTWWSLFRDSMYYI 218

  Fly   184 LIIELVRFFMNDTALAPWIKGAILLSIYPIYLLINIVDLILLR-YAIRKLRADIEVLRQSPSSRE 247
            :.|..:..|:.|..:. |.:..||:.:|..|:||...:..:.| :.|:|     .|....|...|
 Frog   219 ISILALIIFIYDEIIV-WWESLILIVMYFFYILIMKYNTKMQRLFTIKK-----NVGNGCPVGSE 277

  Fly   248 -------HDLILTEKIVRL-------------NNLQQDDEIQILESKLYRKRTYNAGFFVTPK-- 290
                   .|.:..:..|.|             |::...|||.......||.........:|.|
 Frog   278 LQDGNVYSDFVCDDPSVPLLWKVKASQQYYNRNSVVMVDEIICSSPPKYRFPEAGLRIMITNKFP 342

  Fly   291 ---PLIHHKEVDVETNRRILHSKANPKNLFL--FSEFLQ----AINPID-----SEGWYL----- 336
               .|.....:.:...:|:|||........|  ..|.|:    .::..|     :|..||
 Frog   343 PRTRLRMASRLIINERQRLLHSANGTSTTTLDGKQELLENGGLHVDKADDYQEENEANYLVPFSV 407

  Fly   337 -SGTCARILQ-ILKAPVTLMLHLVVPLVDYQLVKHGWSKMLNCLQIVLTPFVIFALVETMLVHKY 399
             || ||.|.: ....|:..:|:..:|               ||.:                 .::
 Frog   408 PSG-CANIFKWAFSWPLICILYFTIP---------------NCSK-----------------PRW 439

  Fly   400 AEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRTDIPPFYHSSYCALTISTVIIFFWICAWEMDALI 464
            ..::.:......:|                                   :.||.:|..|    ::
 Frog   440 ENFFMLTFITSTLW-----------------------------------IAIFSYIMVW----MV 465

  Fly   465 SIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVL 529
            ::||....:....|.|||.:...:..|.:|...:|:.|.|.||....||.:|:.:.|.:|:...|
 Frog   466 TVIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNSIGSNVFDILVGLGVPWGL 530

  Fly   530 QKKLNSRGQVVLYGDDGVTIYIFLVI-TITTTLWWCLTFNFVARRSAGLFMWSLFVLFLVYTTAI 593
            |..:.:.|..|.....|:...:.|:: ::..|:.......:...:..|.::..|:.:||.::..|
 Frog   531 QTMIINYGSTVKINSKGLVYSVILLLGSVALTVGGIYVNKWKLDKKFGFYVLFLYAIFLCFSVLI 595

  Fly   594 E 594
            |
 Frog   596 E 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	ECM27	106..>221	CDD:440296	32/123 (26%)
		PLN03151	<337..529	CDD:215604	33/192 (17%)
		Na_Ca_ex	450..591	CDD:426387	33/141 (23%)
slc24a4	XP_002933272.2	2A1904	<91..596	CDD:273344	116/584 (20%)