Protein Alignment CG14743 and slc24a4b

DIOPT Version :9

• Sequence 1: NP_610408.2
• Gene: CG14743 / 35860
• FlyBaseID: FBgn0033326
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_002665845.2
• Gene: slc24a4b / 100334346
• ZFINID: ZDB-GENE-081031-75
• Length: 636
• Species: Danio rerio
• Alignment Length: 561
• Identity: 114/561 - (20%)
• Similarity: 207/561 - (36%)
• Gaps: 132/561 - (23%)

  Fly    74 VVMLLFALIYCFF-LCILYEGVNSYFAPTLKIAALKMRINEYMAGVVLVGVANSTPDLLVNLSPV 137
            |::.:.|.:|.|. |.|:   .:.||..:|:....|:.::|.:||...:...:|.|:|..::..|
Zfish   153 VLLHIIAALYMFLALAIV---CDDYFVTSLEKICEKLNLSEDVAGATFMAAGSSAPELFASVIGV 214

  Fly   138 RME------GLTFNIAMANALTIICLSGGAVCFI---RPFRMNGHSIFRDLLFLLLIIELVRFFM 193
            .:.      |.....|:.|   |:|:.|  ||.|   :...:...::|||..|.:|.:..:..|:
Zfish   215 FITHGDVGVGTIVGSAVFN---ILCIIG--VCGIFAGQVVLLTWWAVFRDSFFYILSVVALIVFI 274

  Fly   194 NDTALAPWIKGAILLSIYPIYLLINIVDLILLRYAIRKLRADIEVLRQSPSSREHDLILTEKIVR 258
            .|..:. |.:..:|:.:|..|:||...:..|.::..||...::.....:..|...| :.|.||..
Zfish   275 YDEKIV-WWESLVLVVMYACYILIMKFNSRLQKFFTRKGNKNVANGNAAAGSELED-VKTSKIYS 337

  Fly   259 LNNLQQDDEIQILESKLYRKRTYNAGFFVT----PKPLIHHKEVDVETNRRILHSKAN------- 312
            ..::...|||.......||.........||    ||..:......:.|.|:.|...||
Zfish   338 RGSVVMVDEIINASPPNYRFPEAGLRVMVTNHFGPKTRLRMASRLIITERQRLVQSANGVETAVV 402

  Fly   313 -----------PKNLFLFSEFLQAINPIDSEGWYLSGTCARILQILKAPVTLMLHLVVPLVDYQL 366
                       |::.....:..:...|....    .|...|...::..|:.|:|...:|    ..
Zfish   403 DGKPDIENGNVPEDKSTEEKESELTTPFRLP----DGCMNRTKWLISWPLLLILFFTIP----NC 459

  Fly   367 VKHGWSKMLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMA-IWSLLVTMPLAIVVFLHSR 430
            .|..|.|                             |::..|.:: :|
Zfish   460 AKSRWEK-----------------------------YFMLSFILSTVW----------------- 478

  Fly   431 TDIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAY 495
                              :.:|.:...|    :::|||....:....|.|||.:...:..|.||.
Zfish   479 ------------------IAVFSYFMVW----MVTIIGYTLGIPDVIMGITFLAAGTSVPDCIAS 521

  Fly   496 AHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVTIYIFLVI-TITT 559
            ..:|:.|.|.||....||.:|:.:.|.:|:...||....:.|.||:....|:...:.|:: ::..
Zfish   522 LIVARQGLGDMAVSNTIGSNVFDILVGLGVPWALQTMAVNYGSVVMINSRGLLYSVVLLLGSVAL 586

  Fly   560 TL------WWCLTFNFVARRSAGLFMWSLFVLFLVYTTAIE 594
            |:      .|.|.|..      |:::..|:.:||.::..||
Zfish   587 TILGIHLNHWKLDFKL------GVYVLLLYAVFLCFSIMIE 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14743	NP_610408.2	Na_Ca_ex	77..220	CDD:279963	38/152 (25%)
		Na_Ca_ex	450..591	CDD:279963	37/147 (25%)
slc24a4b	XP_002665845.2	TIGR00367	155..581	CDD:273039	103/511 (20%)
		Na_Ca_ex	156..298	CDD:279963	37/150 (25%)
		Na_Ca_ex	467..619	CDD:279963	40/196 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810