DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14744 and AT5G17850

DIOPT Version :9

Sequence 1:	NP_001097232.2	Gene:	CG14744 / 35858	FlyBaseID:	FBgn0033324	Length:	620	Species:	Drosophila melanogaster
Sequence 2:	NP_001318589.1	Gene:	AT5G17850 / 831653	AraportID:	AT5G17850	Length:	559	Species:	Arabidopsis thaliana

Alignment Length:	615	Identity:	132/615 - (21%)
Similarity:	222/615 - (36%)	Gaps:	158/615 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 CRAVMRL-PYNYRCRMATQVSDCKRIINFFNYFRMMYCSIDIDDKATEVLFMLLFAFICVAFLW- 90
            |.|:... .|..:|.....:..|.. ..||:|...:||:.:        .|.:|..|:  .|||
plant    46 CSALKHFHDYKSKCAYLKSIDPCAS-QGFFDYLSFLYCNFE--------GFPILGQFL--LFLWL 99

  Fly    91 -----LMSFNIGTYFSPVLKIISLKLHMNEYLAGVTFLAFGNCSPEIIANLMPVRADAPIFTITV 150
                 |:......||...|:.:|..|:::..:||||.|:.||.:|::.|:|:....::. .|..|
plant   100 LLLFYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFASLVSFMGESK-GTYDV 163

  Fly   151 G-NTLAIILLSGGTVCFL----------RPFRMNGHSTLRDLLFLLLGVEVLRFVMIKEGAVTLG 204
            | ||  ::..||...|.:          |..|:...:.:||:.|....:..|..::: .|.:...
plant   164 GLNT--VVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCAAIGSLALILV-YGKINFW 225

  Fly   205 EGIVLFLIYVVYVAINIADLALLRYYIRKLRRELDYLEGLTPPPITEINAKIRKLISWEEQDDIG 269
            ..:....:|.||||..:                                      :||....|.|
plant   226 GALGFCSLYAVYVAFVV--------------------------------------LSWRFGGDQG 252

  Fly   270 IKDTTKYRRSRDTGNHFSNMTSSGYFVTPIPERRSEHVDYELNRTALHDSE----NPKNLQLFTE 330
            .:            :...::...|....||           |.|..|.:.|    |.:: |:..:
plant   253 AE------------SDLESIHKRGSLSEPI-----------LQRDGLEEIEDGVVNGEH-QIVDD 293

  Fly   331 FFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPFV 395
                    |.:..:...|...:......||.....|.||||..:|    |||.|....:...|.:
plant   294 --------DDDHQRYYYWKRLVIWAITLPLNLPRILTIPVVSEDK----WSKPLAVASVTFAPVL 346

  Fly   396 VITLVHSGVSSVYKTWHITLDFSISMWSPCLT-VPLAIVIFLHSRTDVPPSYHHL-FIILTFFSS 458
            :..|.:      :|....:.:..:.....||. :.|..:....::...||....| ::...|..|
plant   347 LSFLWN------WKRKPTSFEAGVVYLIGCLIGIALGFIAGATTKKLTPPKKWLLPWLAGGFVMS 405

  Fly   459 MVTLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIG- 522
            |...:::..||..|...:|.:|.:|.|.:.:|..|..|:..|:|.|..:||......|..|:.|
plant   406 MTWSYISAQELVALLTSLGYIFGVSPSILGLTVLAWGNSIGDLITNLTMALHDGNEGAQVAVSGC 470

  Fly   523 --GPVFAILVSMSLAFIFNHRVREVGANSW--------------VYGDLGDNCYLFLVITIVTTM 571
              ||:|..|.::.::.        ||. :|              :...||     |||..:|
plant   471 YAGPIFNTLFALGISL--------VGC-AWEAYPLSIVIKTDPRLLESLG-----FLVAGLV--- 518

  Fly   572 WWS--VTFDFHARRSA--GVFLWLVYLQFL 597
             ||  |.|....|...  |:.|.::||..|
plant   519 -WSFLVLFSNRMRLGGVMGIGLLVIYLASL 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14744	NP_001097232.2	Na_Ca_ex	79..221	CDD:279963	41/158 (26%)
CG14744	NP_001097232.2	Na_Ca_ex	450..601	CDD:279963	44/169 (26%)
AT5G17850	NP_001318589.1	PLN03151	34..556	CDD:215604	132/615 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940